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接受定期血液透析治疗的患者的血浆促红细胞生成素水平与获得性肾囊肿疾病

Plasma erythropoietin levels and acquired cystic disease of the kidney in patients receiving regular haemodialysis treatment.

作者信息

Edmunds M E, Devoy M, Tomson C R, Krishna U, Clayworth A, Durrant S T, Feehally J, Walls J

机构信息

Department of Nephrology, Leicester General Hospital.

出版信息

Br J Haematol. 1991 Jun;78(2):275-7. doi: 10.1111/j.1365-2141.1991.tb04428.x.

DOI:10.1111/j.1365-2141.1991.tb04428.x
PMID:2064967
Abstract

Acquired cystic disease of the kidney (ACDK) in patients with end-stage renal failure can be associated with development of polycythaemia. The relationship between plasma erythropoietin levels and ACDK in 17 patients on long-term haemodialysis treatment was studied. There was a significantly higher level of plasma erythropoietin in patients with multiple renal cysts than in those patients with less than five cysts or no cysts. Haemoglobin tended to be higher in the ACDK group, but the difference was not significant. These results indicate that the development of renal cysts results in increased secretion of erythropoietin.

摘要

终末期肾衰竭患者的获得性肾囊肿病(ACDK)可能与红细胞增多症的发生有关。研究了17例长期接受血液透析治疗的患者血浆促红细胞生成素水平与ACDK之间的关系。多发性肾囊肿患者的血浆促红细胞生成素水平显著高于囊肿少于5个或无囊肿的患者。ACDK组的血红蛋白水平倾向于更高,但差异不显著。这些结果表明肾囊肿的形成导致促红细胞生成素分泌增加。

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