Narcotic Analysis Division, Forensic Science Department, National Institute of Scientific Investigation, Seoul 158-707, Republic of Korea.
Forensic Sci Int. 2011 Mar 20;206(1-3):77-80. doi: 10.1016/j.forsciint.2010.06.023. Epub 2010 Jul 21.
The effects of repeated hair washing and a single hair dyeing on concentrations of methamphetamine (MA) and amphetamine (AM) in hair samples of MA addicts were studied. Thirty-one MA positive hair samples collected from male (n = 24, 24-51 yrs) and female abusers (n = 7, 17-46 yrs) were evaluated for MA and AM concentration's changes after repeated hair washing and a single hair dyeing. Thirty-one MA positive hair samples, no additional treatment hair sample group (NAT), were treated in vitro with liquid soap or three kinds of hair dyes which were black, brown and yellow color hair dye, respectively. Quantitation of AM and MA in hair samples was utilized GC-MS using selected ion monitoring. MA and AM concentrations in NAT were 10.41 ± 8.91 ng/mg (range 1.50-30.0 ng/mg) and 2.24 ± 2.75 ng/mg (range 0.41-12.90 ng/mg). And, their concentrations were decreased about 23.3 ± 4.5% (range 16.7-32.8%) in hair repeated washing group (WAS) and 32.6 ± 4.82 (22.2-41.9) in three kinds of a single hair dyeing groups in comparison to original concentrations of MA and AM in NAT. A statistically significant difference was found between NAT and WAS or three hair dyeing groups (p < 0.01), but not between WAS and three hair dyeing groups, and not between each hair dyeing groups with each three kinds of hair dyes (p > 0.05).
研究了反复洗发和单次染发对 MA 成瘾者头发中 MA 和 AM 浓度的影响。评估了 31 份来自男性（n=24，24-51 岁）和女性滥用者（n=7，17-46 岁）的 MA 阳性头发样本中 MA 和 AM 浓度在反复洗发和单次染发后的变化。31 份 MA 阳性头发样本，未经其他处理的头发样本组（NAT），分别用液体肥皂或三种染发剂（黑色、棕色和黄色染发剂）进行体外处理。采用选择离子监测的 GC-MS 定量分析头发样本中的 AM 和 MA。NAT 中 MA 和 AM 的浓度分别为 10.41±8.91ng/mg（范围 1.50-30.0ng/mg）和 2.24±2.75ng/mg（范围 0.41-12.90ng/mg）。与 NAT 中 MA 和 AM 的原始浓度相比，反复洗发组（WAS）中其浓度降低了约 23.3±4.5%（范围 16.7-32.8%），三种单次染发组中降低了 32.6±4.82%（22.2-41.9%）。与 NAT 相比，WAS 或三种染发剂组的 MA 和 AM 浓度均有统计学差异（p<0.01），但 WAS 与三种染发剂组之间以及每种染发剂组之间的差异无统计学意义（p>0.05）。
