Marwan Ahmed, Christein John D
Department of Surgery, University of Alabama at Birmingham, Birmingham, Ala., USA.
Case Rep Gastroenterol. 2009 Apr 17;3(1):92-96. doi: 10.1159/000207440.
Malignant neoplasms of the pancreas are extremely rare in children and only represent a small percentage of pediatric cancer-related deaths. The paucity of cases reported in the literature, in addition to the lack of understanding of biologic behavior, has led to a lack of consensus concerning optimal management strategy. Presentation differs compared to adult counterparts and generally prognosis is improved even when lymph node metastases occur. Here we review the literature and report the case of a 10-year-old autistic female with a malignant nonfunctioning pancreatic endocrine neoplasm of the head of the pancreas successfully extirpated via pancreaticoduodenectomy.
胰腺恶性肿瘤在儿童中极为罕见，仅占儿童癌症相关死亡的一小部分。除了对生物学行为缺乏了解外，文献中报道的病例稀少，导致在最佳治疗策略方面缺乏共识。与成人患者相比，临床表现有所不同，即使发生淋巴结转移，总体预后通常也会改善。在此，我们回顾文献并报告一例10岁患有无功能胰腺内分泌性头侧胰腺恶性肿瘤的自闭症女性患者，经胰十二指肠切除术成功切除肿瘤。
