Toutous-Trellu Laurence, Charlet Isabelle, Hirschel Bernard, Prins C, Masouyé I, Vischer Ulrich M, Janssens Jean-Paul
Department of Dermatology and Venerology, University Hospitals of Geneva, Geneva, Switzerland.
Case Rep Dermatol. 2009 Aug 28;1(1):23-28. doi: 10.1159/000235690.
Skin localizations in disseminated tuberculosis may present a clinical resistant evolution. An 81-year-old woman, treated by long-term steroids and methotrexate for rheumatoid polyarthritis, developed a disseminated tuberculosis in chest, bones and skin. While pulmonary symptoms quickly improved under conventional tuberculostatic drugs, skin ulcers showed positive cultures for 5 months and healed after 12 months of treatment.
播散性结核病的皮肤病变可能呈现临床耐药演变。一名81岁女性，因类风湿性多关节炎长期接受类固醇和甲氨蝶呤治疗，出现了胸部、骨骼和皮肤的播散性结核病。虽然在常规抗结核药物治疗下肺部症状迅速改善，但皮肤溃疡培养5个月呈阳性，治疗12个月后愈合。
