Tartaglione A, Inglese M L, Bandini F, Spadavecchia L, Hamsher K, Favale E
Clinica Neurologica dell'Universitá di Genova, Italy.
Brain. 1991 Jun;114 ( Pt 3):1441-56. doi: 10.1093/brain/114.3.1441.
Thirty control subjects and 60 unilateral brain-damaged patients, 30 with left hemisphere (LH) damage and 30 with right hemisphere (RH) disease, underwent a disjunctive 4-choice reaction time study. Speed of reaction (as defined by the reciprocal of reaction time (RT), movement time (MT) and total response time (TRT] and accuracy of response (as represented by the sum of errors in selecting the correct response key) were investigated comparatively as a function of side of lesion and of performance on Raven's Coloured Progressive Matrices (PM47). In contrast to movement speed (1/MT), reaction speed (1/RT) as well as total response speed (1/TRT) showed a lesion effect independent of side of damage. Conversely, accuracy was differentially impaired, LH damage being associated with a significantly higher number of errors. Speed and accuracy had different relationships with the performance on the PM47 in the two hemisphere groups. Speed was affected in parallel with changes in PM47 performance both in the LH and in RH groups, whereas accuracy was altered only in LH patients. It was concluded that speed of motor reaction is affected by unilateral brain lesions irrespective of their side, whereas decision making processes, as expressed by accuracy of response, seem to be specifically impaired by LH damage.
30名对照受试者和60名单侧脑损伤患者（30例左半球[LH]损伤，30例右半球[RH]病变）接受了一项析取式四选一反应时研究。比较研究了反应速度（由反应时[RT]、运动时[MT]和总反应时[TRT]的倒数定义）和反应准确性（由选择正确反应键时的错误总和表示）作为损伤侧别和瑞文彩色渐进矩阵测试（PM47）表现的函数。与运动速度（1/MT）不同，反应速度（1/RT）以及总反应速度（1/TRT）显示出与损伤侧别无关的损伤效应。相反，准确性受到不同程度的损害，LH损伤与显著更多的错误相关。在两个半球组中，速度和准确性与PM47测试表现的关系不同。LH组和RH组的速度都与PM47测试表现的变化平行受到影响，而准确性仅在LH患者中发生改变。研究得出结论，单侧脑损伤会影响运动反应速度，而与损伤侧别无关，而以反应准确性表示的决策过程似乎特别受到LH损伤的损害。
