Departamento de Química Inorgánica y Orgánica, Universitat Jaume I, 12071-Castellón, Spain.
Chemistry. 2010 Sep 10;16(34):10502-6. doi: 10.1002/chem.201000801.
A new tandem catalytic process has been studied for a heterodimetallic complex containing both iridium and palladium fragments connected by a 1,2,4-trimethyltriazolyldiylidene ligand. The process implies the unprecedented preparation of imines from the direct reaction of nitroarenes and primary alcohols. The global process comprises the following steps: 1) reduction of the nitroarene to an amine, 2) oxidation of the alcohol to aldehyde, and 3) condensation of the aldehyde and the amine to form the corresponding imine. The oxidation of the alcohol to aldehyde is promoted by the iridium fragment, while the reduction of the nitro group to amine is facilitated by palladium. A wide set of different catalytic systems has been studied, showing that the Ir/Pd complex 1 is a highly active and stable catalyst in the preparation of imines.
一种新型的串联催化过程已经被研究用于一种包含铱和钯片段的杂二金属配合物，这些片段通过 1,2,4-三甲基三唑二亚基配体连接。该过程意味着前所未有的直接由硝基芳烃和伯醇制备亚胺。整个过程包括以下步骤：1）将硝基芳烃还原为胺，2）将醇氧化为醛，3）将醛和胺缩合形成相应的亚胺。醇的氧化由铱片段促进，而硝基还原为胺则由钯促进。已经研究了广泛的不同催化体系，表明 Ir/Pd 配合物 1 是制备亚胺的高效稳定催化剂。
