Guío Felipe, Rodríguez Mauro A, Alméciga-Diaz Carlos J, Sánchez Oscar F
Department of Chemical and Environmental Engineering, Universidad Nacional de Colombia, Bogotá, Colombia.
Recent Pat Food Nutr Agric. 2009 Nov;1(3):221-30. doi: 10.2174/2212798410901030221.
Prebiotics are food ingredients that promote host health beneficially due to their effect over the growth and activity of probiotic bacterial species. Prebiotic properties have been demonstrated for inulin-type fructans, galactoolicosaccharides and lactulose. Fructooligosaccharides (FOS), considered as inulin-type fructans, represent an important source of prebiotic compounds that are widely used as an ingredient in functional foods. FOS are produced by the action of fructosyltransferase from many plants, fungi and bacteria, and they are mainly composed of 1-kestose, nystose, and 1-beta-fructofuranosyl nystose. Among them, 1-kestose has better therapeutic properties than those with a high polymeric degree (GF(n > 4)). FOS exhibited properties than those with a high polymeric degree (GF(n>4)). FOS exhibited properties such as low caloric values, non-cariogenic properties, decrease levels of lipids and cholesterol, help gut absorption of ions, and stimulate the bifidobacteria growth in the human colon. This review presents a summary of the patents related with FOS production by industrial sucrose biotransformation or the use of recombinant fructosyltransferase enzymes. Also, a brief description of recent FOS applications will be discussed.
益生元是一类食品成分，由于它们对益生菌种的生长和活性产生影响，从而对宿主健康产生有益作用。菊粉型果聚糖、低聚半乳糖和乳果糖已被证明具有益生元特性。低聚果糖（FOS）被认为是菊粉型果聚糖，是益生元化合物的重要来源，被广泛用作功能性食品的一种成分。FOS是由许多植物、真菌和细菌中的果糖基转移酶作用产生的，它们主要由蔗果三糖、棉子糖和1-β-呋喃果糖基棉子糖组成。其中，蔗果三糖比高聚合度（GF(n > 4)）的那些具有更好的治疗特性。FOS表现出低热量值、非致龋性、降低脂质和胆固醇水平、有助于肠道对离子的吸收以及刺激人结肠中双歧杆菌生长等特性。本综述总结了与通过工业蔗糖生物转化或使用重组果糖基转移酶生产FOS相关的专利。此外，还将讨论FOS近期应用的简要描述。
