UCLA Cardiac Arrhythmia Center, David Geffen School of Medicine at UCLA, Los Angeles, CA90095-1679, USA.
J Cardiovasc Electrophysiol. 2011 Jan;22(1):49-56. doi: 10.1111/j.1540-8167.2010.01859.x.
Ultra High-Density Multipolar Mapping With Double Ventricular Access.
Analogous to the use of circular loop catheters to guide ablation around the pulmonary veins, it may be advantageous to use a multipolar catheter in the ventricle for rapid mapping and to guide ablation. We describe a technique using double access into the left ventricle for multipolar electroanatomic mapping and ablation of scar-mediated ventricular tachycardia (VT).
Double access into the left ventricle was obtained via transseptal technique. Endocardial mapping was performed via the first transseptal sheath using a steerable duodecapolar catheter. Higher density mapping was performed in areas of dense scar (<0.5 mV) and border zone (0.5-1.5 mV). All late potentials (LPs) observed on the 20 poles were tagged and pacemapping was performed at these sites for comparison with the clinical or induced VT 12-lead template. If VT was hemodynamically tolerated, entrainment mapping was attempted at sites demonstrating diastolic activity. Ablation was performed through the second transseptal sheath with an open-irrigated catheter at target sites identified by LPs, pacemapping, and/or entrainment on the duodecapolar catheter.
Seventeen patients (88% ischemic cardiomyopathy) underwent electroanatomic mapping and ablation with double transseptal access. The mean number of endocardial mapping points was 819 ± 357 with an average mapping time of 31 ± 7 minutes. The mean number of VTs induced was 2.8 ± 1.6, mean cycle length 418 ms ± 101. LPs were seen in all patients during endocardial mapping with the duodecapolar catheter. Good (56%) and perfect (44%) pacemaps were seen in all patients when performed. Concealed entrainment, guided by the earliest diastolic activity seen on the duodecapolar catheter, was demonstrated in 4 patients (24%). Acute success was achieved in 94% of patients with complete success in 47% and partial success in 47%. The intermediate success rate (free of VT recurrence) was 69%, with an average follow-up of 8 ± 3 months.
Mapping and ablation of scar-mediated VT using a multipolar catheter results in ultra high-density delineation of the left ventricular substrate. A novel double ventricular access strategy has the potential to facilitate identification of LPs, pacemapping, and entrainment mapping.
标题:双心室入路的超高密度多极标测
背景:类似于使用环形环导管引导肺静脉周围消融,使用心室中的多极导管进行快速标测和指导消融可能是有利的。我们描述了一种使用双心室入路进行多极电生理标测和瘢痕介导性室性心动过速(VT)消融的技术。
方法:通过经房间隔技术获得双心室入路。通过第一个经房间隔鞘管使用可转向的十二极导管进行心内膜标测。在高密度瘢痕(<0.5 mV)和交界区(0.5-1.5 mV)进行高密度标测。观察到的所有晚期电位(LP)在 20 个极上标记,并在这些部位进行起搏标测,与临床或诱发性 VT12 导联模板进行比较。如果 VT 血流动力学耐受,尝试在表现为舒张期活动的部位进行拖带标测。通过第二个经房间隔鞘管,使用在十二极导管上通过 LP、起搏标测和/或拖带识别的目标部位的开放灌洗导管进行消融。
结果:17 名患者(88%缺血性心肌病)接受了双经房间隔心内膜标测和消融。平均心内膜标测点数为 819±357,平均标测时间为 31±7 分钟。平均诱发性 VT 数为 2.8±1.6,平均心动周期长度为 418 ms±101。在使用十二极导管进行心内膜标测时,所有患者均可见 LP。所有患者均可进行良好(56%)和完美(44%)起搏标测。在 4 名患者(24%)中,通过在十二极导管上观察到的最早舒张期活动,显示隐匿性拖带。94%的患者获得了急性成功,其中 47%为完全成功,47%为部分成功。中间成功率(无 VT 复发)为 69%,平均随访 8±3 个月。
结论:使用多极导管对瘢痕介导性 VT 进行标测和消融可实现左心室基质的超高密度描绘。新型双心室入路策略有可能促进 LP、起搏标测和拖带标测的识别。