药师管理的皮下储库醋酸甲羟孕酮:一项试点随机对照试验。

Pharmacist-administered subcutaneous depot medroxyprogesterone acetate: a pilot randomized controlled trial.

机构信息

Department of Social Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, USA.

出版信息

Contraception. 2010 Aug;82(2):160-7. doi: 10.1016/j.contraception.2010.01.013. Epub 2010 Feb 19.

Abstract

BACKGROUND

The objectives of this study were to assess the feasibility of administering subcutaneous depot medroxyprogesterone acetate (DMPA-SC) in a pharmacy setting and assess patient satisfaction.

STUDY DESIGN

Fifty women, at least 18 years of age, presenting to a family planning clinic to initiate, continue or restart any form of DMPA were randomized to receive two subsequent injections at a nearby pharmacy by trained pharmacists or at the clinic. Women completed two follow-up surveys to rate their satisfaction with DMPA-SC and their clinic/pharmacy experiences.

RESULTS

The relative risk of returning and receiving a second DMPA-SC injection of women randomized to the pharmacy compared with those randomized to the clinic was 0.73 (95% CI 0.42-1.27). The relative risk of returning and receiving a third DMPA-SC injection was 0.75 (95% CI 0.39-1.46). Most women found the pharmacy setting convenient (70%), private (100%), the providers respectful (100%) and were satisfied with DMPA-SC and the pharmacy as a clinical site (> or = 89%). No significant difference in patient satisfaction with location, convenience, privacy, and respect from providers was found between study groups (p>.05), nor were there significant differences in attitudes or satisfaction among women between their two follow-up injections.

CONCLUSION

Administration of DMPA-SC by pharmacists in a pharmacy setting is feasible. Continuation rates and patient satisfaction with DMPA-SC and the pharmacy setting were comparable to those who received DMPA-SC in a family planning clinic.

摘要

背景

本研究旨在评估在药房环境下皮下注射 depot 醋酸甲羟孕酮(DMPA-SC)的可行性,并评估患者满意度。

研究设计

50 名年龄至少 18 岁的女性,因开始、继续或重新使用任何形式的 DMPA 而前往计划生育诊所,将其随机分配至由训练有素的药剂师在附近药房或诊所接受随后的两次注射。女性完成了两次随访调查,以评估她们对 DMPA-SC 和诊所/药房体验的满意度。

结果

与随机分配至诊所的女性相比,随机分配至药房的女性返回并接受第二次 DMPA-SC 注射的相对风险为 0.73(95%CI 0.42-1.27)。返回并接受第三次 DMPA-SC 注射的相对风险为 0.75(95%CI 0.39-1.46)。大多数女性认为药房环境便利(70%)、私密(100%)、提供者尊重(100%),并对 DMPA-SC 和药房作为临床场所非常满意(≥89%)。研究组之间在患者对地点、便利性、隐私和提供者尊重的满意度方面无显著差异(p>.05),女性在两次随访注射之间的态度或满意度也无显著差异。

结论

在药房环境下由药剂师管理 DMPA-SC 是可行的。DMPA-SC 的续用率和患者对 DMPA-SC 和药房环境的满意度与在计划生育诊所接受 DMPA-SC 的患者相当。

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