Chih An-Hsuan, Jan Chyi-Feng, Shu San-Ging, Lue Bee-Horng
Department of Family Medicine, National Taiwan University Hospital, Taipei, Taiwan.
J Formos Med Assoc. 2010 Jul;109(7):503-10. doi: 10.1016/S0929-6646(10)60084-8.
BACKGROUND/PURPOSE: Self-management is crucial to diabetes control. To investigate the effectiveness of self-management in reaching target hemoglobin A1c (HbA1c) level, we conducted a study among Taiwanese adolescents with type 1 diabetes mellitus (DM).
Patients aged 12-20 years with type 1 DM participated in an annual integrated DM care clinic at a medical center in Taiwan. All patients completed a questionnaire that included demographic data and self-efficacy measured by the Perceived Diabetes Self-Management Scale (PDSMS) in February 2008. Laboratory tests were also done at the same visit. The target HbA1c was < 7.0% in accordance with the general standard of the American Diabetes Association for patients with type 1 DM. Logistic regression analysis was used to explore the relationship between age, sex, duration of diabetes, PDSMS score, and HbA1c level.
Fifty-two patients were enrolled. The mean age was 16.0 +/- 2.4 years, and mean HbA1c level was 8.6 +/- 1.6%. Pearson correlation analysis showed a positive correlation between body mass index and preprandial blood sugar level (r = 0.297, p < 0.05). Negative correlations were found between PDSMS scores and duration of diabetes (r = -0.365, p < 0.01) as well as HbA1c level (r = -0.295, p < 0.05). Logistic regression analysis demonstrated that sex and PDSMS scores significantly influenced glycemic control. In multivariate logistic regression analysis, patients with higher PDSMS scores were 1.63 times (95% confidence interval = 1.03-2.59) more likely to reach target diabetes control after adjustment for other variables. Male patients also had a higher probability (odds ratio = 19.80, 95% confidence interval = 1.34-291.93) of reaching target diabetes control.
This study demonstrates that adolescents with type 1 DM and higher self-efficacy, especially males, have a higher probability of reaching target diabetes control.
背景/目的:自我管理对糖尿病控制至关重要。为了研究自我管理在达到目标糖化血红蛋白(HbA1c)水平方面的有效性,我们在台湾1型糖尿病(DM)青少年中开展了一项研究。
年龄在12至20岁的1型糖尿病患者参加了台湾一家医疗中心的年度综合糖尿病护理门诊。所有患者于2008年2月完成了一份问卷,其中包括人口统计学数据以及通过糖尿病自我管理感知量表(PDSMS)测量的自我效能感。在同一次就诊时还进行了实验室检查。根据美国糖尿病协会针对1型糖尿病患者的一般标准,目标HbA1c低于7.0%。采用逻辑回归分析来探讨年龄、性别、糖尿病病程、PDSMS评分与HbA1c水平之间的关系。
共纳入52例患者。平均年龄为16.0±2.4岁,平均HbA1c水平为8.6±1.6%。Pearson相关分析显示体重指数与餐前血糖水平呈正相关(r = 0.297,p < 0.05)。PDSMS评分与糖尿病病程(r = -0.365,p < 0.01)以及HbA1c水平(r = -0.295,p < 0.05)呈负相关。逻辑回归分析表明性别和PDSMS评分对血糖控制有显著影响。在多变量逻辑回归分析中,调整其他变量后,PDSMS评分较高的患者达到糖尿病控制目标的可能性是前者的1.63倍(95%置信区间 = 1.03 - 2.59)。男性患者达到糖尿病控制目标的概率也更高(优势比 = 19.80,95%置信区间 = 1.34 - 291.93)。
本研究表明,自我效能感较高的1型糖尿病青少年,尤其是男性,达到糖尿病控制目标的概率更高。