Wand Benedict Martin, Parkitny Luke, O'Connell Neil Edward, Luomajoki Hannu, McAuley James Henry, Thacker Michael, Moseley G Lorimer
School of Health Sciences, The University of Notre Dame Australia, Fremantle, WA, Australia.
Man Ther. 2011 Feb;16(1):15-20. doi: 10.1016/j.math.2010.06.008. Epub 2010 Jul 23.
There is increasing evidence that chronic pain problems are characterised by alterations in brain structure and function. Chronic back pain is no exception. There is a growing sentiment, with accompanying theory, that these brain changes contribute to chronic back pain, although empirical support is lacking. This paper reviews the structural and functional changes of the brain that have been observed in people with chronic back pain. We cast light on the clinical implications of these changes and the possibilities for new treatments but we also advise caution against concluding their efficacy in the absence of solid evidence to this effect.
越来越多的证据表明，慢性疼痛问题的特征是脑结构和功能的改变。慢性背痛也不例外。尽管缺乏实证支持，但有一种观点及其相关理论越来越流行，即这些脑部变化会导致慢性背痛。本文综述了在慢性背痛患者中观察到的脑部结构和功能变化。我们阐明了这些变化的临床意义以及新治疗方法的可能性，但我们也建议在没有确凿证据的情况下，谨慎得出关于其疗效的结论。
