Norwegian University of Science and Technology, Norway.
Cephalalgia. 2010 Aug;30(8):904-9. doi: 10.1177/0333102409356023. Epub 2010 Mar 12.
Normal heat pain threshold (HPT) and cold pain threshold (CPT) repeatability should be estimated in order to identify thermal allodynia in longitudinal studies, but such data are scarce in the literature. The aim of our study was to estimate normal HPT and CPT repeatability in the face, forehead, neck and hand. In addition, we reviewed briefly normative studies of thermal pain thresholds relevant for headache research. Thermal pain thresholds were measured on three different days in 31 healthy headache-free subjects. Coefficients of repeatability and normal limits were calculated. HPT and CPT were lowest in the face. Pooled across regions, the lower repeatability limit for the test/retest ratio was 63% for HPT and 55% for CPT. The upper normal CPT limit varied between 24.5 degrees C and 29.7 degrees C. Lower HPT limits ranged between 35.5 degrees C and 40.8 degrees C. Quantitative sensory methods provide useful information about headache and pain pathophysiology, and it is important to estimate the normal test/retest repeatability range in follow-up studies.
为了在纵向研究中识别热痛觉过敏，应该估计正常的热痛觉阈值（HPT）和冷痛觉阈值（CPT）的可重复性，但文献中此类数据很少。我们的研究目的是评估面部、前额、颈部和手部的正常 HPT 和 CPT 可重复性。此外，我们还简要回顾了与头痛研究相关的热痛阈值的正常性研究。在 31 名无头痛的健康受试者中，在三天的不同时间测量了热痛阈值。计算了可重复性系数和正常限值。HPT 和 CPT 在面部最低。在所有区域中，HPT 的测试/复测比值的较低可重复性限值为 63%，CPT 的为 55%。CPT 的正常上限范围在 24.5°C 到 29.7°C 之间。HPT 的下限范围在 35.5°C 到 40.8°C 之间。定量感觉方法为头痛和疼痛病理生理学提供了有用的信息，在随访研究中估计正常的测试/复测可重复性范围很重要。
