University Centre for Adaptive Disorders and Headache, Italy.
Cephalalgia. 2010 Aug;30(8):987-90. doi: 10.1177/0333102409357478. Epub 2010 Mar 17.
SUNCT syndrome (short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing) is a primary headache characterised by a high frequency of attacks associated with marked autonomic periocular signs and symptoms. Activation of the hypothalamus via the superior salivary nucleus is probably responsible for some of the autonomic involvement observed during SUNCT attacks. We describe a case of SUNCT with unusual autonomic features (e.g., mydriasis) and early onset. Pupillometric studies were performed both in a basal condition (without anisocoria) and after instillation of phenylephrine (a drug with direct sympathomimetic activity) and pilocarpine (a parasympathetic agonist). The findings in this patient seem to indicate involvement of the ocular sympathetic supply in SUNCT, responsible for the mydriasis, and seem to strengthen the possibility that the autonomic phenomena in this syndrome vary with different levels of pain severity.
丛集性头痛（发作性单侧头痛伴有结膜充血和流泪）是一种原发性头痛，其特点是发作频率高，伴有明显的眼周自主征象和症状。下丘脑通过上涎核的激活可能是 SUNCT 发作期间观察到的一些自主参与的原因。我们描述了一例具有不常见自主特征（例如瞳孔散大）和早期发病的丛集性头痛病例。在基础状态（无瞳孔不等大）和苯肾上腺素滴注（一种具有直接拟交感神经活性的药物）以及毛果芸香碱滴注（一种副交感神经激动剂）后进行瞳孔测量研究。该患者的发现似乎表明，在 SUNCT 中，眼部交感神经供应参与了瞳孔散大，并似乎加强了这样一种可能性，即该综合征中的自主现象随疼痛严重程度的不同而变化。
