Kumar Ashok J, Leeds Norman E, Kumar Vinodh A, Fuller Gregory N, Lang Frederick F, Milas Zvonimir, Weinberg Jeffrey S, Ater Joann L, Sawaya Raymond
Division of Diagnostic Imaging, University of Texas, MD Anderson Cancer Center, Houston, TX 77030, USA.
J Comput Assist Tomogr. 2010 Jul;34(4):601-11. doi: 10.1097/RCT.0b013e3181d77d52.
The typical magnetic resonance/computed tomographic imaging appearance of pilocytic astrocytoma (PA) is that of a cyst with an intensely enhancing mural nodule. The purpose of this study was to illustrate the aggressive imaging features of PA.
One hundred patients referred to the cancer center with brain tumors histologically proven to be PA were retrospectively reviewed (95 by magnetic resonance imaging and 5 by computed tomographic imaging) and analyzed.
The patient population includes 76 pediatric patients younger than 18 years and 24 adults ranging from 19 to 45 years old. Tumor locations consisted of the following: optic chiasm (22), lateral ventricle (3), thalamus (12), basal ganglia (1), cerebral hemisphere (10), corpus callosum (2), brain stem (26), fourth ventricle (1), and cerebellum (23). The imaging appearance of PA consisted of typical features in 71 cases and aggressive features in 29 cases.
It is important to recognize the aggressive imaging appearance of PA (grade 1 astrocytoma) because it can be mistaken for high-grade gliomas and may thus lead to inappropriate therapy. Despite the aggressive imaging appearance of PA, there is no histopathologic evidence of anaplasia.
毛细胞型星形细胞瘤（PA）典型的磁共振成像/计算机断层扫描表现为有一个强化明显的壁结节的囊肿。本研究的目的是阐述PA的侵袭性影像学特征。
对100例转诊至癌症中心、经组织学证实为PA的脑肿瘤患者进行回顾性研究（95例行磁共振成像检查，5例行计算机断层扫描检查）并分析。
患者群体包括76例18岁以下的儿童患者和24例年龄在19至45岁之间的成人患者。肿瘤部位包括：视交叉（22例）、侧脑室（3例）、丘脑（12例）、基底神经节（1例）、大脑半球（10例）、胼胝体（2例）、脑干（26例）、第四脑室（1例）和小脑（23例）。PA的影像学表现71例为典型特征，29例为侵袭性特征。
认识PA（1级星形细胞瘤）的侵袭性影像学表现很重要，因为它可能被误诊为高级别胶质瘤，从而可能导致不适当的治疗。尽管PA有侵袭性影像学表现，但没有间变的组织病理学证据。
