Murahashi Takeo, Sato Kenichi, Ito Tamio, Ozaki Yoshimaru, Sugio Hironori, Nakamura Hirohiko, Tanaka Shinya
Department of Neurosurgery, Nakamura Memorial Hospital, Japan.
No Shinkei Geka. 2012 Sep;40(9):793-7.
Pilocytic astrocytoma is the most common glioma in children, in whom the majority arise in the cerebellum. In contrast, pilocytic astrocytomas are less common in adults. The most frequent locations involved are the basal ganglia, cerebellum, optic chiasm, and hypothalamus. Overall survival rates are good. The case presented involved a pilocytic astrocytoma of the right parietal lobe in a 36-year-old man. Cranial magnetic resonance imaging (MRI) revealed a small mural nodule in the wall of the cyst, with no edema around the tumor. This nodule showed a hyperintense signal on gadolinium-enhanced MRI. Computed tomography (CT) scanning revealed a hypodense right parietal lobe mass with calcification. At surgery, the cyst contents were aspirated, and the mural nodule was excised. Postoperative radiotherapy was not given. Neuropathological examination revealed a pilocytic astrocytoma (Grade I). The MIB-index was 3.3%. There has been no recurrence after 1 year of postoperative follow-up.
毛细胞型星形细胞瘤是儿童最常见的胶质瘤,其中大多数发生在小脑。相比之下,毛细胞型星形细胞瘤在成人中较少见。最常累及的部位是基底神经节、小脑、视交叉和下丘脑。总体生存率良好。所报告的病例为一名36岁男性的右顶叶毛细胞型星形细胞瘤。头颅磁共振成像(MRI)显示囊肿壁上有一个小的壁结节,肿瘤周围无水肿。该结节在钆增强MRI上呈高信号。计算机断层扫描(CT)显示右顶叶有一个低密度肿块伴钙化。手术时,抽出囊肿内容物,并切除壁结节。未给予术后放疗。神经病理学检查显示为毛细胞型星形细胞瘤(I级)。MIB指数为3.3%。术后随访1年无复发。