Department of Neurosurgery, Toshiba Stroke Research Center, School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, 14209, USA.
Neurosurgery. 2010 Sep;67(3):794-8; discussion 798. doi: 10.1227/01.NEU.0000374724.78276.A6.
To describe the technique of endovascular access for treatment of vasospasm of a radial artery bypass graft from the occipital artery to the M3 branch of the middle cerebral artery (MCA) in a patient with moyamoya disease.
A 32-year-old woman presented with recurrent right-sided ischemic symptoms in the territory of a previous stroke. Angiographic findings were consistent with moyamoya disease, and a perfusion deficit was identified on computed tomography (CT) perfusion imaging.
The patient underwent a left MCA bypass graft for flow augmentation. She returned with an occluded bypass graft, collateralization of the anterior MCA territory through a spontaneous synangiosis, and a severe perfusion deficit in the posterior MCA territory. She underwent a revision bypass graft procedure with the radial artery from the occipital artery stump to the MCA-M3 branch. She developed repeated symptomatic vasospasm of the radial artery graft postoperatively. After systemic anticoagulation, the graft was accessed through the occipital artery, and intra-arterial verapamil was injected. When this failed to resolve the graft spasm, the radial artery graft was accessed with a 0.14-inch Synchro-2 microwire (Boston Scientific, Natick Massachusetts), and sequential angioplasties were performed using over-the-wire balloons from the proximal to distal anastomosis and in the occipital artery stump. A nitroglycerin patch was applied cutaneously over the graft to relieve the vasospasm.
No complications occurred. Graft patency with robust flow was observed on the 5-month follow-up angiogram.
Endovascular techniques can be safely used for salvage of spastic extracranial-intracranial grafts.
描述治疗烟雾病患者枕动脉至大脑中动脉(MCA)M3 分支桡动脉旁路移植术后血管痉挛的血管内入路技术。
一名 32 岁女性因先前中风区域反复发作右侧缺血症状而就诊。血管造影结果符合烟雾病,计算机断层扫描(CT)灌注成像显示存在灌注不足。
患者接受了左侧 MCA 旁路移植术以增加血流量。她因闭塞的旁路移植术、前 MCA 区域通过自发吻合的侧支循环以及后 MCA 区域严重的灌注不足而返回。她接受了桡动脉从枕动脉残端至 MCA-M3 分支的再修复旁路移植术。她术后反复出现桡动脉移植术血管痉挛的症状。在全身抗凝后,通过枕动脉进入移植术,并注入了动脉内维拉帕米。当这未能解决移植术痉挛时,用 0.14 英寸的 Synchro-2 微导丝(波士顿科学公司,马萨诸塞州纳提克)进入桡动脉移植术,并从近端至远端吻合口和枕动脉残端依次进行球囊血管成形术。在移植术上贴硝酸甘油贴片以缓解血管痉挛。
无并发症发生。在 5 个月的随访血管造影中观察到移植术通畅且血流丰富。
血管内技术可安全用于治疗痉挛性颅内外移植术。