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EGF receptor induction and insulin-EGF overlap in Tetrahymena.

作者信息

Csaba G, Kovács P

机构信息

Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.

出版信息

Experientia. 1991 Jul 15;47(7):718-21. doi: 10.1007/BF01958825.

DOI:10.1007/BF01958825
PMID:2065769
Abstract

Offspring generations of Tetrahymena pretreated (imprinted) with insulin showed a greater binding capacity for the hormone than offspring of untreated ones. The epidermal growth factor (EGF) imprinted for insulin to a greater degree than insulin itself, and vice versa: insulin imprinted for EGF more efficiently than EGF itself. These phenomena can be explained by the overlap of insulin and EGF on one another's receptors in Tetrahymena.

摘要

相似文献

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本文引用的文献

1
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Effects of epidermal growth factor (urogastrone) on gluconeogenesis, glucose oxidation, and glycogen synthesis in isolated rat hepatocytes.表皮生长因子(尿抑胃素)对离体大鼠肝细胞糖异生、葡萄糖氧化及糖原合成的影响。
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Evidence of the receptor nature of the binding sites induced in Tetrahymena by insulin treatment. A quantitative cytofluorimetric technique for the study of binding kinetics.
Cell Biochem Funct. 1990 Jan;8(1):49-56. doi: 10.1002/cbf.290080108.
7
The NSILA-s receptor in liver plasma membranes. Characterization and comparison with the insulin receptor.肝细胞膜中的NSILA-s受体。特性及其与胰岛素受体的比较。
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