Center for Environmental Research, Tehran University of Medical Sciences, Tehran, Iran.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2010 Oct;27(10):1460-8. doi: 10.1080/19440049.2010.495730.
A reliable and sensitive method for simultaneous determination of bisphenol A (BPA) and bisphenol F (BPF) in canned food by gas chromatography-mass spectrometry (GC/MS) is described after extraction and pre-concentration by a new solid-phase microextraction (SPME) adsorbent. The potential of single-walled carbon nanotubes (SWCNTs) as SPME adsorbent for the pre-concentration of environmental contaminants has been investigated in recent years. This work was carried out to investigate the feasibility of SWCNTs as a headspace SPME adsorbent for the determination of bisphenol derivatives in canned food. Potential factors affecting the extraction efficiency, including extraction time, extraction temperature, desorption time, desorption temperature, and salinity were optimized. Calibration curves were linear (r(2)> or = 0.994) over the concentration range from 0.30 to 60 microg kg(-1). For both target analytes, the limit of detection (LOD) at signal-to-noise (S/N) ratio of 3 was 0.10 microg kg(-1). In addition, a comparative study between the SWCNT and a commercial polydimethylsiloxane (PDMS) SPME fibre for the determination of bisphenol derivatives in canned food was conducted. SWCNT fibre showed higher extraction capacity, better thermal stability (over 350 degrees C) and longer life span (over 150 times) than the commercial PDMS fibre. The method was successfully applied to determine BPA in canned food samples which were purchased from local markets. BPA was found in some of the samples within the concentration range from 0.5 to 5.2 microg kg(-1).
一种可靠且灵敏的方法，用于通过气相色谱-质谱法（GC/MS）从罐头食品中提取和预浓缩后同时测定双酚 A（BPA）和双酚 F（BPF）。近年来，单壁碳纳米管（SWCNT）作为固相微萃取（SPME）吸附剂用于浓缩环境污染物的潜力已得到研究。这项工作旨在研究 SWCNT 作为顶空 SPME 吸附剂用于测定罐头食品中双酚衍生物的可行性。对影响萃取效率的潜在因素（包括萃取时间、萃取温度、解吸时间、解吸温度和盐度）进行了优化。在 0.30 至 60μgkg(-1)的浓度范围内，校准曲线呈线性（r(2)≥0.994）。对于这两种目标分析物，信噪比（S/N）为 3 时的检出限（LOD）为 0.10μgkg(-1)。此外，还对 SWCNT 和商业聚二甲基硅氧烷（PDMS）SPME 纤维在测定罐头食品中双酚衍生物方面进行了比较研究。SWCNT 纤维的萃取容量更高，热稳定性更好（超过 350°C），使用寿命更长（超过 150 次），优于商业 PDMS 纤维。该方法成功应用于测定从当地市场购买的罐头食品中的 BPA。在一些样品中发现 BPA 的浓度范围为 0.5 至 5.2μgkg(-1)。
