Department of Psychiatry, Hirosaki-Aiseikai Hospital, Hirosaki, Japan.
Int J Geriatr Psychiatry. 2011 Apr;26(4):409-14. doi: 10.1002/gps.2541.
Apathy is defined as a lack of interest or emotion. Several studies have shown the relationship between apathy and atherosclerotic change in poststroke patients. Although apathy is confused with depression, it might be a specific neuropsychiatric syndrome separate from depression.
To clarify the relationship between atherosclerotic change and apathy in a community-dwelling population, which does not include the psychologic factors associated with stroke events.
The ankle brachial pressure index (ABI) was measured using a volume-plethymographic apparatus in 860 volunteers (315 males and 545 females) who participated in the Iwaki Health Promotion Project 2008. Starkstein's apathy score and the Center for Epidemiologic Studies Depression Scale (CES-D) were used to assess the psychologic status. The association between the ABI and apathy was assessed by a multiple linear regression analysis.
Gender and low-density lipoprotein (LDL)-cholesterol were independently and significantly associated with the CES-D score. We did not find any association between CES-D score and the ABI. In addition, the extent of education and the ABI were independently and significantly associated with the apathy scale (AS).
In a community-dwelling population, a lower ABI score was an independent risk factor for a higher AS score, but not for a higher CES-D score. Apathy and depression may have different etiologies in vascular factors.
冷漠定义为缺乏兴趣或情感。多项研究表明，冷漠与脑卒中患者的动脉粥样硬化变化之间存在关系。尽管冷漠与抑郁相混淆，但它可能是一种与抑郁不同的特定神经精神综合征。
在不包括与卒中事件相关的心理因素的社区居民中，阐明动脉粥样硬化变化与冷漠之间的关系。
在参加 2008 年岩木健康促进计划的 860 名志愿者（315 名男性和 545 名女性）中，使用容积脉搏描记仪测量踝臂血压指数（ABI）。使用 Starkstein 的冷漠评分和流行病学研究中心抑郁量表（CES-D）评估心理状态。通过多元线性回归分析评估 ABI 与冷漠之间的关系。
性别和低密度脂蛋白（LDL）-胆固醇与 CES-D 评分独立且显著相关。我们没有发现 CES-D 评分与 ABI 之间存在任何关联。此外，教育程度和 ABI 与冷漠量表（AS）独立且显著相关。
在社区居民中，较低的 ABI 评分是 AS 评分较高的独立危险因素，但不是 CES-D 评分较高的独立危险因素。冷漠和抑郁在血管因素方面可能具有不同的病因。
