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自体干细胞移植作为复发性胰胚细胞瘤患者的治疗方式。

Autologous stem cell transplantation as treatment modality in a patient with relapsed pancreatoblastoma.

机构信息

Hematology-Oncology and Stem Cell Transplantation Research Center, Tehran University of Medical Sciences, Shariati Hospital, Tehran, Iran.

出版信息

Pediatr Blood Cancer. 2010 Sep;55(3):573-6. doi: 10.1002/pbc.22536.

Abstract

Pancreatoblastoma (PB) is a rare malignant neoplasm of the pancreas, which occurs mostly during childhood. Presently, the optimal treatment strategy is neither clear nor uniform for patients in advanced stages, in particular those with metastasis, inoperable, or recurrent tumors. To our knowledge, until now, only one patient with PB has been treated with hematopoietic stem cell transplantation (HSCT) following aggressive chemotherapy and surgical resection. Here we report the second case of PB who was treated with aggressive chemotherapy combined with autologous peripheral blood stem cell transplantation.

摘要

胰腺母细胞瘤(PB)是一种罕见的胰腺恶性肿瘤,主要发生在儿童时期。目前,对于晚期患者,特别是转移、无法手术或复发性肿瘤患者,尚无明确且统一的最佳治疗策略。据我们所知,到目前为止,仅有一例 PB 患者在强化化疗和手术切除后接受了造血干细胞移植(HSCT)治疗。在此,我们报告了第二例接受强化化疗联合自体外周血干细胞移植治疗的 PB 患者。

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