Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, No. 2 Yuanmingyuan West Road, Haidian District, Beijing 100193, PR China.
Virus Res. 2010 Dec;154(1-2):31-7. doi: 10.1016/j.virusres.2010.07.016. Epub 2010 Jul 24.
Porcine reproductive and respiratory syndrome (PRRS) is an economically important viral disease for the pig industry worldwide. This disease has brought great losses to the Chinese pig production in recent years, particularly following the emergence of the highly pathogenic PRRS virus (PRRSV), and has become an intractable problem for the development of pig industry in China. This paper will review the history of PRRS, the epidemic of atypical PRRS caused by the highly pathogenic virus, and the molecular characteristics of the Chinese highly pathogenic PRRSV, and the development of vaccines against PRRS in China, as well as current control status and perspective of PRRS in China.
猪繁殖与呼吸综合征（PRRS）是一种对全球养猪业具有重要经济意义的病毒性疾病。近年来，该疾病给中国的养猪生产带来了巨大损失，尤其是高致病性 PRRS 病毒（PRRSV）的出现，已成为中国养猪业发展的一个难题。本文将回顾 PRRS 的历史、高致病性病毒引起的非典型 PRRS 的流行情况以及中国高致病性 PRRSV 的分子特征，介绍中国 PRRS 疫苗的研发进展，以及目前中国 PRRS 的防控现状和展望。
