Research Institute for Fragrance Materials, Inc., 50 Tice Boulevard, Woodcliff Lake, NJ 07677, USA.
Food Chem Toxicol. 2010 Jul;48 Suppl 4:S47-50. doi: 10.1016/j.fct.2010.05.026.
A toxicologic and dermatologic review of 3,5,5-trimethyl-1-hexanol when used as a fragrance ingredient is presented. 3,5,5-Trimethyl-1-hexanol is a member of the fragrance structural group branched chain saturated alcohols. The common characteristic structural elements of the alcohols with saturated branched chain are one hydroxyl group per molecule, and a C(4) to C(12) carbon chain with one or several methyl side chains. This review contains a detailed summary of all available toxicology and dermatology papers that are related to this individual fragrance ingredient and is not intended as a stand-alone document. A safety assessment of the entire branched chain saturated alcohol group will be published simultaneously with this document; please refer to Belsito et al. (2010) for an overall assessment of the safe use of this material and all other branched chain saturated alcohols in fragrances.
当 3,5,5-三甲基-1-己醇用作香料成分时，对其进行了毒理学和皮肤学评估。3,5,5-三甲基-1-己醇是香料结构组支链饱和醇的成员。具有饱和支链的醇的常见特征结构元素是每个分子一个羟基和一个 C(4)至 C(12)碳原子链，带有一个或几个甲基侧链。本综述包含了与该特定香料成分相关的所有可用毒理学和皮肤学论文的详细总结，但不作为独立文件。整个支链饱和醇组的安全性评估将与本文件同时发布；请参阅 Belsito 等人（2010 年），以全面评估该物质以及香料中所有其他支链饱和醇的安全使用情况。
