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足病主导的肢体保全团队对糖尿病下肢疾病结局及风险预测的影响:一项回顾性队列研究

The impact of a podiatric lead limb preservation team on disease outcomes and risk prediction in the diabetic lower extremity: a retrospective cohort study.

作者信息

Driver Vickie R, Goodman Russell A, Fabbi Matteo, French Michael A, Andersen Charles A

机构信息

Limb Preservation Service, Department of Vascular Surgery, Madigan Army Medical Center, Tacoma, WA, USA.

出版信息

J Am Podiatr Med Assoc. 2010 Jul-Aug;100(4):235-41. doi: 10.7547/1000235.

Abstract

BACKGROUND

We used a model of lower-extremity ulceration to determine the impact of a podiatric lead limb preservation team on identified relationships among risk factors, predictors of ulceration, amputation, and clinical outcomes of lower-extremity disease in patients with diabetes mellitus.

METHODS

A total of 485 patients with diabetes mellitus were randomly selected from the diabetic population and included in this retrospective cohort study. Patients were then stratified into two groups: those who received specialty podiatric medical care and those who did not. Data covering a 5-year period were collected using electronic medical records and chart abstraction to capture detailed treatment characteristics, ulcer status, and surgical outcomes.

RESULTS

Overall, the frequencies of inpatient and outpatient encounters and the durations of hospital stays were significantly greater with increasing wound depth and in the presence of infection. In addition, the overall ulcer incidence was greater in patients with callus (34.3% versus 10.3%, P < .0001) with and without neuropathy (20.4% and 4.1%, P < .0001). Among patients treated in a specialty multidiscipline podiatric medical setting, the proportion of all amputations that were "minor" was significantly increased (33.7% versus 67.3%, P = .0006), and survival was significantly improved (19.5% versus 7.7%, P < .0001).

CONCLUSIONS

Early identification of individuals at increased risk for lower-extremity ulceration and subsequent referral for advanced multidiscipline podiatric medical specialty care may decrease rates of ulceration and proximal amputation and improve survival in patients with diabetes mellitus who are at high risk for ulceration and limb loss.

摘要

背景

我们采用下肢溃疡模型来确定足病主导的肢体保全团队对已明确的糖尿病患者风险因素、溃疡预测因素、截肢情况以及下肢疾病临床结局之间关系的影响。

方法

从糖尿病患者群体中随机选取485例患者纳入这项回顾性队列研究。然后将患者分为两组:接受专科足病医疗护理的患者和未接受专科足病医疗护理的患者。利用电子病历和病历摘要收集涵盖5年期间的数据,以获取详细的治疗特征、溃疡状态和手术结局。

结果

总体而言,随着伤口深度增加以及存在感染时,住院和门诊就诊频率以及住院时间显著更长。此外,有胼胝的患者总体溃疡发生率更高(34.3% 对10.3%,P <.0001),无论有无神经病变(分别为20.4% 和4.1%,P <.0001)。在接受专科多学科足病医疗的患者中,所有“小”截肢的比例显著增加(33.7% 对67.3%,P =.0006),生存率显著提高(19.5% 对7.7%,P <.0001)。

结论

早期识别下肢溃疡风险增加的个体,并随后转诊接受高级多学科足病专科护理,可能会降低溃疡和近端截肢发生率,并提高溃疡和肢体缺失高风险糖尿病患者的生存率。

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