Brdicka R
Ustav Hematologie a Krevní Transfuze a Ustav Experimentální Mediciny AV CR, Praha.
Cas Lek Cesk. 2009;148(10):477-80.
Personalized medicine has become declared to be a strategic goal of nearly all medical disciplines, a modern fashion of medicine, which corresponds to unexpected progress in knowledge of structure and sometimes also understanding the function of our genome. This was made possible by development of new technologies and methodological approaches, which led to improved and more detailed diagnostics and categorization of diseases. Also pharmaceutical industry is producing many new drugs, but not all are effective as supposed, and sometimes also cause adverse reactions (ADR). To prevent uneffectiveness and ADR, preliminary genetic testing of patients seems to be necessary. Utility of personalized medicine is sometimes discussed from the point of view of supposed inevitable increase of cost and problems with its adoption by existing system of healthcare.
个性化医疗已被宣布为几乎所有医学学科的战略目标,是一种现代医学潮流,这与我们在基因组结构知识方面取得的意想不到的进展以及有时对其功能的理解相对应。新技术和方法学途径的发展使这成为可能,这些技术和途径带来了改进的、更详细的疾病诊断和分类。制药行业也在生产许多新药,但并非所有药物都如预期那样有效,有时还会引起不良反应(ADR)。为了预防无效性和不良反应,对患者进行初步基因检测似乎是必要的。有时会从成本必然增加以及现有医疗保健系统采用个性化医疗存在问题的角度来讨论其效用。