辅助病毒对艾贝尔逊病毒诱导的淋巴细胞转化的影响。
The effect of helper virus on Abelson virus-induced transformation of lymphoid cells.
作者信息
Rosenberg N, Baltimore D
出版信息
J Exp Med. 1978 Apr 1;147(4):1126-41. doi: 10.1084/jem.147.4.1126.
Abstract
Abelson murine leukemia virus (A-MuLV)-transformed fibroblast nonproducer cells were used to prepare A-MuLV stocks containing a number of different helper viruses. The oncogenicity of the A-MuLV stocks was tested by animal inoculation and their ability to transform normal mouse bone marrow cells was measured in vitro. All of the A-MuLV stocks transformed fibroblast cells efficiently. However, only A-MuLV stocks prepared with helper viruses that are highly oncogenic were efficient in vivo and in vitro in hematopoietic cell transformation. In addition, inefficient helpers did not establish a stable infection in lymphoid nonproducer cells. Thus, helper virus has a more central role in lymphoid cell transformation than in fibroblast cell transformation.
摘要
阿贝尔森鼠白血病病毒（A-MuLV）转化的成纤维细胞非生产性细胞被用于制备含有多种不同辅助病毒的A-MuLV病毒株。通过动物接种测试了A-MuLV病毒株的致癌性，并在体外测量了它们转化正常小鼠骨髓细胞的能力。所有的A-MuLV病毒株都能有效地转化成纤维细胞。然而，只有用具有高度致癌性的辅助病毒制备的A-MuLV病毒株在体内和体外的造血细胞转化中才有效。此外，低效的辅助病毒在淋巴非生产性细胞中不能建立稳定的感染。因此，辅助病毒在淋巴细胞转化中比在成纤维细胞转化中起着更核心的作用。
相似文献
1
The effect of helper virus on Abelson virus-induced transformation of lymphoid cells.辅助病毒对艾贝尔逊病毒诱导的淋巴细胞转化的影响。
J Exp Med. 1978 Apr 1;147(4):1126-41. doi: 10.1084/jem.147.4.1126.
2
Effect of pseudotype on Abelson virus and Kirsten sarcoma virus-induced leukemia.假型对阿贝尔森病毒和柯斯顿肉瘤病毒诱导的白血病的影响。
J Exp Med. 1978 Apr 1;147(4):1044-53. doi: 10.1084/jem.147.4.1044.
3
Abelson murine leukemia virus: effect of helper virus from regressing Friend virus on leukemia development.阿贝尔森鼠白血病病毒：来自消退型弗瑞德病毒的辅助病毒对白血病发展的影响。
Leuk Res. 1983;7(2):251-60. doi: 10.1016/0145-2126(83)90015-2.
4
Cell transformation and tumor induction by Abelson murine leukemia virus in the absence of helper virus.在无辅助病毒情况下，艾贝尔逊鼠白血病病毒诱导的细胞转化和肿瘤形成
Proc Natl Acad Sci U S A. 1987 Aug;84(16):5932-6. doi: 10.1073/pnas.84.16.5932.
5
Virus production by Abelson murine leukemia virus-transformed lymphoid cells.阿贝尔森鼠白血病病毒转化的淋巴样细胞产生病毒
J Virol. 1979 Aug;31(2):557-67. doi: 10.1128/JVI.31.2.557-567.1979.
6
Distinct helper virus requirements for Abelson murine leukemia virus-induced pre-B- and T-cell lymphomas.阿贝尔逊鼠白血病病毒诱导前B细胞和T细胞淋巴瘤对不同辅助病毒的需求
J Virol. 1989 May;63(5):2088-98. doi: 10.1128/JVI.63.5.2088-2098.1989.
7
Identification of an Abelson murine leukemia virus-encoded protein present in transformed fibroblast and lymphoid cells.在转化的成纤维细胞和淋巴细胞中存在的一种阿贝尔逊鼠白血病病毒编码蛋白的鉴定。
Proc Natl Acad Sci U S A. 1978 May;75(5):2488-92. doi: 10.1073/pnas.75.5.2488.
8
Helper virus is not required for in vitro erythroid transformation of hematopoietic cells by Friend virus.弗氏病毒对造血细胞进行体外红系转化时无需辅助病毒。
Proc Natl Acad Sci U S A. 1980 Sep;77(9):5287-91. doi: 10.1073/pnas.77.9.5287.
9
10
Abelson murine leukemia virus variants with increased oncogenic potential.具有增强致癌潜力的阿贝尔逊鼠白血病病毒变体。
J Virol. 1986 Nov;60(2):599-606. doi: 10.1128/JVI.60.2.599-606.1986.
引用本文的文献
1
Antiretroviral drug-S for a possible HIV elimination.用于实现可能的消除艾滋病病毒目标的抗逆转录病毒药物-S
Int J Physiol Pathophysiol Pharmacol. 2019 Aug 15;11(4):149-162. eCollection 2019.
2
and isoforms are both efficient to drive B cell differentiation.并且异构体在驱动B细胞分化方面都很有效。
Oncotarget. 2018 Aug 28;9(67):32841-32854. doi: 10.18632/oncotarget.26003.
3
The helper virus envelope glycoprotein affects the disease specificity of a recombinant murine leukemia virus carrying a v-myc oncogene.辅助病毒包膜糖蛋白影响携带v-myc癌基因的重组鼠白血病病毒的疾病特异性。
Virus Genes. 2001 Jun;22(3):311-9. doi: 10.1023/a:1011166323566.
4
Identification of Bach2 as a B-cell-specific partner for small maf proteins that negatively regulate the immunoglobulin heavy chain gene 3' enhancer.鉴定Bach2为小maf蛋白的B细胞特异性伙伴，其对免疫球蛋白重链基因3'增强子起负调控作用。
EMBO J. 1998 Oct 1;17(19):5734-43. doi: 10.1093/emboj/17.19.5734.
5
A requirement for NF-kappaB activation in Bcr-Abl-mediated transformation.Bcr-Abl介导的细胞转化中NF-κB激活的必要条件。
Genes Dev. 1998 Apr 1;12(7):968-81. doi: 10.1101/gad.12.7.968.
6
BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.BCR-ABL和v-abl癌基因诱导涉及不同淋巴细胞亚群的不同胸腺淋巴瘤模式。
J Virol. 1993 Oct;67(10):6033-46. doi: 10.1128/JVI.67.10.6033-6046.1993.
7
A complex of glycoproteins is associated with VpreB/lambda 5 surrogate light chain on the surface of mu heavy chain-negative early precursor B cell lines.一种糖蛋白复合物与μ重链阴性早期前体B细胞系表面的VpreB/λ5替代轻链相关联。
J Exp Med. 1993 Aug 1;178(2):469-78. doi: 10.1084/jem.178.2.469.
8
Selective repression of v-abl-encoded protein by N-methylisatin-beta-4',4'-diethylthiosemicarbazone and N-allylisatin-beta-4',4'-diallylthiosemicarbazone.N-甲基异靛红-β-4',4'-二乙硫代氨基脲和N-烯丙基异靛红-β-4',4'-二烯丙硫代氨基脲对v-abl编码蛋白的选择性抑制作用
Antimicrob Agents Chemother. 1993 Nov;37(11):2483-5. doi: 10.1128/AAC.37.11.2483.
9
Molecular cloning of infectious ecotropic murine leukemia virus AK7 from an emv-14-positive AKXL-5 mouse and the resistance of AK7 to recognition by cytotoxic T lymphocytes.从一只emv - 14阳性的AKXL - 5小鼠中克隆出感染性亲嗜性鼠白血病病毒AK7及其对细胞毒性T淋巴细胞识别的抗性。
J Virol. 1993 Aug;67(8):5045-50. doi: 10.1128/JVI.67.8.5045-5050.1993.
10
Pathogenic determinants in the U3 region of recombinant murine leukemia viruses isolated from CWD and HRS/J mice.从慢性消耗病（CWD）和HRS/J小鼠中分离出的重组鼠白血病病毒U3区域的致病决定因素。
J Virol. 1994 Aug;68(8):5174-83. doi: 10.1128/JVI.68.8.5174-5183.1994.
本文引用的文献
1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
ASSAY FOR FRIEND LEUKEMIA VIRUS: RAPID QUANTITATIVE METHOD BASED ON ENUMERATION OF MACROSCOPIC SPLEEN FOCI IN MICE.Friend白血病病毒检测：基于小鼠脾脏肉眼可见病灶计数的快速定量方法。
Virology. 1964 Nov;24:513-8. doi: 10.1016/0042-6822(64)90199-0.
3
4
Rescue of the defective genome of Moloney sarcoma virus from a noninfectious hamster tumor and the production of pseudotype sarcoma viruses with various murine leukemia viruses.从非感染性仓鼠肿瘤中拯救莫洛尼肉瘤病毒的缺陷基因组，并利用各种鼠白血病病毒生产假型肉瘤病毒。
Proc Natl Acad Sci U S A. 1966 Oct;56(4):1164-9. doi: 10.1073/pnas.56.4.1164.
5
Rapid cell culture assay technic for murine leukaemia viruses.鼠白血病病毒的快速细胞培养测定技术
Nature. 1971 Feb 19;229(5286):564-6. doi: 10.1038/229564b0.
6
Spontaneous segregation of nontransforming viruses from cloned sarcoma viruses.非转化病毒从克隆肉瘤病毒中的自发分离。
Virology. 1971 Dec;46(3):939-46. doi: 10.1016/0042-6822(71)90092-4.
7
Rescue of murine sarcoma virus from a sarcoma-positive leukemia-negative cell line: requirement for replicating leukemia virus.从肉瘤阳性白血病阴性细胞系中拯救鼠肉瘤病毒：对复制性白血病病毒的需求。
J Virol. 1971 Nov;8(5):690-4. doi: 10.1128/JVI.8.5.690-694.1971.
8
Murine sarcoma virus transformation of BALB-3T3 cells: lack of dependence on murine leukemia virus.BALB - 3T3细胞的鼠肉瘤病毒转化：不依赖鼠白血病病毒。
Proc Natl Acad Sci U S A. 1970 Aug;66(4):1236-43. doi: 10.1073/pnas.66.4.1236.
9
Isolation of murine sarcoma virus-transformed mouse cells which are negative for leukemia virus from agar suspension cultures.从琼脂悬浮培养物中分离白血病病毒呈阴性的鼠肉瘤病毒转化的小鼠细胞。
Int J Cancer. 1970 Jul 15;6(1):95-107. doi: 10.1002/ijc.2910060114.
10
Nonproducer clones of murine sarcoma virus transformed BALB-3T3 cells.鼠肉瘤病毒转化的BALB-3T3细胞的非产生性克隆。
Virology. 1970 Sep;42(1):9-19. doi: 10.1016/0042-6822(70)90233-3.
Zotero 插件