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利多卡因注射治疗枕神经痛的枕神经阻滞的不良反应特征。

Adverse effect profile of lidocaine injections for occipital nerve block in occipital neuralgia.

机构信息

Department of Neurology, Keck School of Medicine, University of Southern California, 1100 North State St, Room A4E111, Los Angeles, CA 90033, USA.

出版信息

J Headache Pain. 2010 Dec;11(6):519-23. doi: 10.1007/s10194-010-0244-x. Epub 2010 Jul 28.

Abstract

To determine whether there are differences in the adverse effect profile between 1, 2 and 5% Lidocaine when used for occipital nerve blocks (ONB) in patients with occipital neuralgia. Occipital neuralgia is an uncommon cause of headaches. Little is known regarding the safety of Lidocaine injections for treatment in larger series of patients. Retrospective chart analysis of all ONB was performed at our headache clinic during a 6-year period on occipital neuralgia patients. 89 consecutive patients with occipital neuralgia underwent a total of 315 ONB. All the patients fulfilled the IHS criteria for Occipital Neuralgia. Demographic data were collected including age, gender, and ethnicity. The average age of this cohort was 53.25 years, and the majority of patients were females 69 (78%). Ethnicity of patients was diverse, with Caucasian 48(54%), Hispanics 31(35%), and others 10 (11%). 69 patients had 1%, 18 patients had 2% and 29 patient were given 5% Lidocaine. All Lidocaine injections were given with 20 mg Depo-medrol and the same injection technique and location were used for all the procedures. Eight patients (9%)had adverse effects to the Lidocaine and Depo-medrol injections, of which 5 received 5% and 3 received 1% Lidocaine. Majority of patients who had adverse effects were female 7(87%), and had received bilateral blocks (75%). ONB is a safe procedure with 1% Lidocaine; however, caution should be exerted with 5% in elderly patients, 70 or older, especially when administering bilateral injections.

摘要

为了确定在治疗枕神经痛时,1%、2%和 5%利多卡因用于枕神经阻滞(ONB)的不良影响谱是否存在差异。枕神经痛是一种罕见的头痛原因。关于利多卡因注射治疗更大系列患者的安全性知之甚少。在我们的头痛诊所,对 6 年内所有接受枕神经痛治疗的患者进行了回顾性图表分析。89 例连续的枕神经痛患者共进行了 315 次 ONB。所有患者均符合 IHS 枕神经痛标准。收集了人口统计学数据,包括年龄、性别和种族。该队列的平均年龄为 53.25 岁,大多数患者为女性 69 例(78%)。患者的种族多样,包括白人 48 例(54%)、西班牙裔 31 例(35%)和其他种族 10 例(11%)。69 例患者接受 1%利多卡因,18 例患者接受 2%利多卡因,29 例患者接受 5%利多卡因。所有利多卡因注射均与 20mg 地塞米松混合,所有操作均采用相同的注射技术和位置。8 例(9%)患者对利多卡因和地塞米松注射有不良反应,其中 5 例接受 5%利多卡因,3 例接受 1%利多卡因。有不良反应的大多数患者为女性 7 例(87%),并接受了双侧阻滞(75%)。1%利多卡因用于 ONB 是安全的;然而,在老年患者(70 岁或以上),尤其是双侧注射时,应谨慎使用 5%利多卡因。

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