Department of Anesthesiology, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.
Department of Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing 100070, China.
Pain Res Manag. 2021 Apr 19;2021:5572121. doi: 10.1155/2021/5572121. eCollection 2021.
The therapeutic effectiveness and safety of occipital nerve blockade (ONB) on occipital neuralgia- (ON-) like acute postcraniotomy headache (ON-APCH) was evaluated.
Persistent occipital neuralgia is a subclassification of chronic postcraniotomy headache and has been investigated sporadically in previous publications. The long-lasting neuralgic pain significantly impairs postoperative recovery and quality of life. However, little is known regarding ON-APCH and its management.
All data were retrospectively acquired from consultation records and electronic institutional medical documents. Forty-one patients, who developed drug-resistant ON-APCH after elective craniotomy and received ONB with lidocaine for diagnoses, were included in this study, all of whom were treated using dexamethasone and lidocaine. Pain intensity and ONB correlated complications and side effects were collected and analyzed at three different time points: before ONB, at 1 day after ONB, and at discharge.
Nineteen males and twenty-two females aged 49.6 ± 15.2 years were diagnosed with drug-resistant ON-APCH. The mean NRS was 8.0 ± 0.9 before ONB, which later significantly decreased to 2.1 ± 1.4 and 1.6 ± 0.6 at 1 day after ONB and on discharge, respectively. At 1 month after ONB, thirty patients (73%) obtained complete pain relief without medication. At 3 months after ONB, only two (5%) patients had to continue oral medications to maintain pain relief. No adverse effects or complications were observed immediately after, or within 3 months, of the nerve blockade.
For drug-resistant ON-APCH, early occipital nerve blockade with dexamethasone and lidocaine is an effective and safe technique, which provides adequate pain relief and may prevent further development of persistent presentation of refractory ON.
评估枕神经阻滞(ONB)治疗类枕神经痛(ON-)样急性颅脑手术后头痛(ON-APCH)的疗效和安全性。
持续性枕神经痛是慢性颅脑手术后头痛的一个亚分类,在以前的出版物中曾有零星报道。这种持久的神经痛会显著影响术后恢复和生活质量。然而,对于 ON-APCH 及其管理,我们知之甚少。
所有数据均从会诊记录和电子机构医疗文档中回顾性获得。本研究共纳入 41 例接受择期开颅手术后出现药物难治性 ON-APCH 的患者,这些患者均接受利多卡因行 ONB 以明确诊断,且均接受地塞米松和利多卡因治疗。收集并分析疼痛强度和 ONB 相关并发症及不良反应在三个不同时间点(行 ONB 前、行 ONB 后 1 天、出院时)的数据。
19 名男性和 22 名女性患者的年龄为 49.6±15.2 岁,均被诊断为药物难治性 ON-APCH。行 ONB 前的平均 NRS 为 8.0±0.9,随后在 ONB 后 1 天和出院时分别显著降至 2.1±1.4 和 1.6±0.6。在 ONB 后 1 个月,30 例(73%)患者完全缓解疼痛,无需服药。在 ONB 后 3 个月,仅有 2 例(5%)患者需要继续口服药物以维持疼痛缓解。在神经阻滞后即刻或 3 个月内,均未观察到不良反应或并发症。
对于药物难治性 ON-APCH,早期使用地塞米松和利多卡因行枕神经阻滞是一种有效且安全的技术,可提供充分的疼痛缓解,并可能预防难治性持续性 ON 的进一步发展。