School of Mechanical and Aerospace Engineering, Seoul National University, Seoul 151-742, Korea.
J Am Chem Soc. 2010 Aug 18;132(32):10964-6. doi: 10.1021/ja102673m.
It has been known that single-strand DNA wraps around a single-walled carbon nanotube (SWNT) by pi-stacking. In this paper it is demonstrated that such DNA is dissociated from the SWNT by Watson-Crick base-pairing with a complementary sequence. Measurement of field effect transistor characteristics indicates a shift of the electrical properties as a result of this "unwrapping" event. We further confirm the suggested process through Raman spectroscopy and gel electrophoresis. Experimental results are verified in view of atomistic mechanisms with molecular dynamics simulations and binding energy analyses.
已知单链 DNA 通过π-堆积缠绕在单壁碳纳米管（SWNT）上。本文证明，这种 DNA 通过与互补序列的 Watson-Crick 碱基配对从 SWNT 上解离。场效应晶体管特性的测量表明，这种“解缠”事件导致了电学性质的变化。我们通过拉曼光谱和凝胶电泳进一步证实了所提出的过程。实验结果通过分子动力学模拟和结合能分析从原子机制的角度进行了验证。
