Lorette Gérard, Georgesco Gabriella
Université François-Rabelais (Tours), service de dermatologie, CHU Trousseau, 37044 Tours cedex, France.
Presse Med. 2010 Oct;39(10):1076-80. doi: 10.1016/j.lpm.2010.03.026. Epub 2010 Jul 27.
The linear IgA bullous dermatosis can have various aspects involving erythema and bullous lesions. It is a rare disease. Two peaks of frequency are noticed in children before puberty and in adults around 60 years of age. The histological and immunological characterisation is infraepidermal bullous lesions and linear deposits of IgA along the dermoepidermal basement membrane. There are some targets antigens. There is often a medical condition that seems to trigger. The link with drugs in particular with vancomycin was established. The mainstay of treatment is dapsone generally associated with steroids.