Argenyi Z B, Bergfeld W F, Valenzuela R, McMahon J T, Tomecki K J
Department of Pathology, University of Iowa Hospitals and Clinics, Iowa City 52242.
Int J Dermatol. 1987 Oct;26(8):513-7. doi: 10.1111/j.1365-4362.1987.tb02292.x.
This report describes a 49-year-old woman with an erythema multiforme--like rash and direct immunofluorescence showing linear IgA deposits at the dermoepidermal junction. Light microscopy revealed features of bullous pemphigoid, dermatitis herpetiformis, and erythema multiforme; immunoelectron microscopy demonstrated IgA deposition beneath the lamina densa about anchoring fibrils. These data provide additional information about the variable clinical and histologic manifestations of the adult linear IgA bullous dermatosis and emphasize the diagnostic dilemmas of light microscopy, which are resolved by immunohistochemical methods.
本报告描述了一名49岁女性，其患有多形红斑样皮疹，直接免疫荧光显示在真皮表皮交界处有线性IgA沉积。光镜检查显示有大疱性类天疱疮、疱疹样皮炎和多形红斑的特征；免疫电子显微镜显示IgA沉积于致密板下方的锚定原纤维处。这些数据提供了关于成人线状IgA大疱性皮肤病可变临床和组织学表现的更多信息，并强调了光镜检查的诊断困境，而免疫组化方法可解决这些困境。
