Design of enzyme inhibitors using iterative protein crystallographic analysis.

作者信息

Appelt K, Bacquet R J, Bartlett C A, Booth C L, Freer S T, Fuhry M A, Gehring M R, Herrmann S M, Howland E F, Janson C A

机构信息

Agouron Pharmaceuticals, Inc., La Jolla, California 92037.

出版信息

J Med Chem. 1991 Jul;34(7):1925-34. doi: 10.1021/jm00111a001.

DOI:10.1021/jm00111a001

PMID:2066965

Abstract

摘要

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Design of enzyme inhibitors using iterative protein crystallographic analysis.

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