Seymour Robin A
School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4BW, UK.
Dent Update. 2010 Jun;37(5):279-80, 282-3. doi: 10.12968/denu.2010.37.5.279.
Poor oral health has been associated with a variety of systemic diseases. More recent evidence suggests that the extent and severity of periodontal disease and tooth loss may be associated with an increased risk of malignant disease. An association between poor oral health, smoking, increased alcohol consumption as a risk for oral cancer is well established. Associations between oral health and tooth loss with gastric, lung and pancreatic cancers are explored. Some of the associations need further evaluation before patients are warned about their periodontal health increasing the risk of malignant changes elsewhere in the body. The smoking factor may have a commonality linking oral health with an increased risk for malignant disease.
This paper reviews the association between oral health (especially the extent and severity of periodontal disease and tooth loss) as a risk for certain malignancies.
口腔健康状况不佳与多种全身性疾病有关。最近的证据表明,牙周病的范围和严重程度以及牙齿脱落可能与恶性疾病风险增加有关。口腔健康状况不佳、吸烟、饮酒增加作为口腔癌风险之间的关联已得到充分证实。本文探讨了口腔健康和牙齿脱落与胃癌、肺癌和胰腺癌之间的关联。在向患者警告其牙周健康会增加身体其他部位发生恶性病变的风险之前,其中一些关联需要进一步评估。吸烟因素可能是将口腔健康与恶性疾病风险增加联系起来的一个共性因素。
本文综述了口腔健康(尤其是牙周病的范围和严重程度以及牙齿脱落)作为某些恶性肿瘤风险的关联。