Non-Invasive Imaging Laboratories, Section of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois, USA.
Curr Opin Cardiol. 2010 Sep;25(5):445-50. doi: 10.1097/HCO.0b013e32833cb252.
Right-ventricular (RV) function has both diagnostic and prognostic relevance; thus the ability to accurately evaluate and quantify the RV is critical. Nuclear techniques provide an accurate and reproducible assessment of RV systolic function. Additionally, nuclear techniques can assess RV physiology, thus providing insight into the pathogenesis of common conditions affecting the RV. In this review, we describe the role of nuclear imaging in assessing RV systolic function, perfusion, and metabolism.
Nuclear techniques to quantify RV function have been available for many years, but newer methods to evaluate RV function are emerging. Recent investigations into the pathophysiology of RV failure from a variety of causes have identified RV ischemia and alterations in RV metabolism as major contributors. Because nuclear-imaging techniques also allow evaluation of RV ischemia and metabolism, nuclear imaging may allow a comprehensive assessment of RV function and physiology.
In addition to providing a reliable determination of RV systolic function, nuclear-imaging techniques are emerging as clinically useful tools to assess RV perfusion and metabolism. As these novel uses of nuclear imaging for RV assessment continue to be studied and validated across a variety of clinical settings, an expanded role of nuclear imaging of the RV is anticipated.
右心室（RV）功能具有诊断和预后相关性；因此，准确评估和量化 RV 的能力至关重要。核技术可提供 RV 收缩功能的准确和可重复的评估。此外，核技术还可以评估 RV 的生理学，从而深入了解影响 RV 的常见疾病的发病机制。在这篇综述中，我们描述了核成像在评估 RV 收缩功能、灌注和代谢中的作用。
多年来，已有多种定量 RV 功能的核技术，但评估 RV 功能的新方法正在出现。最近对各种原因引起的 RV 衰竭的病理生理学的研究表明，RV 缺血和 RV 代谢改变是主要原因。由于核成像技术还可以评估 RV 缺血和代谢，因此核成像可能允许对 RV 功能和生理学进行全面评估。
除了提供 RV 收缩功能的可靠测定外，核成像技术作为评估 RV 灌注和代谢的临床有用工具正在出现。随着这些核成像在 RV 评估中的新用途在各种临床环境中不断得到研究和验证，预计 RV 的核成像将发挥更大的作用。
