Bodenant Marie, Leys Didier, Lucas Christian
Department of Neurology, University of Lille, Roger Salengro Hospital, Lille, France.
Case Rep Neurol. 2010 Jun 8;2(2):80-84. doi: 10.1159/000315865.
Cerebral hyperperfusion syndrome is a rare but well-described complication following carotid endarterectomy or stenting. Clinical signs are ipsilateral, throbbing, unilateral headache with nausea or vomiting, seizures, and neurological deficits, with or without intracerebral abnormalities on CT scan, such as brain edema or intracerebral hemorrhage. Subarachnoidal hemorrhage is rarely described especially if it occurs isolated. We describe a 74-year-old man with a history of high blood pressure, hypercholesterolemia, atrioventricular block with pacemaker, and ischemic cardiopathy with coronary bypass. He underwent right carotid endarterectomy for a 90% NASCET asymptomatic stenosis. Four days after surgery, he complained of unusual headaches with right, throbbing hemicrania. Nine days after surgery, he presented with left hemiplegia and a partial motor seizure. He had fluctuant altered consciousness, left hemiplegia, and left visual and sensory neglect. Brain CT showed right frontal subarachnoidal hemorrhage without parenchymal bleeding. Cerebral angiography found no cerebral aneurysm, no vascular malformation, but a vasospasm of the left middle cerebral artery. Transcranial Doppler confirmed this vasospasm. Evolution was favorable with no recurrence of seizures but with an improvement of the neurological deficits and vasospasm. Physicians should bear in mind this very rare complication of endarterectomy and immediately perform neuroimaging in case of unusual headache following endarterectomy or angioplasty.
脑灌注过多综合征是颈动脉内膜切除术或支架置入术后一种罕见但已被充分描述的并发症。临床症状为同侧搏动性单侧头痛,伴有恶心或呕吐、癫痫发作及神经功能缺损,CT扫描时脑内可出现或不出现异常,如脑水肿或脑出血。蛛网膜下腔出血很少见,尤其是孤立发生时。我们报告一名74岁男性,有高血压、高胆固醇血症、带起搏器的房室传导阻滞及冠状动脉搭桥术后缺血性心脏病病史。他因一处90%北美症状性颈动脉内膜切除术(NASCET)标准的无症状狭窄接受了右侧颈动脉内膜切除术。术后4天,他主诉右侧搏动性偏头痛,头痛异常。术后9天,他出现左侧偏瘫和部分运动性癫痫发作。他有意识状态波动、左侧偏瘫以及左侧视觉和感觉忽视。脑部CT显示右侧额叶蛛网膜下腔出血,无实质内出血。脑血管造影未发现脑动脉瘤、血管畸形,但发现左侧大脑中动脉痉挛。经颅多普勒证实了这种血管痉挛。病情好转,癫痫未复发,神经功能缺损和血管痉挛有所改善。医生应牢记这种内膜切除术非常罕见的并发症,在内膜切除术或血管成形术后出现异常头痛时应立即进行神经影像学检查。