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西班牙人嗜T淋巴细胞病毒1型/2型感染的患病率:一项基于医院的横断面调查。

Prevalence of HTLV-1/2 infections in Spain: A cross-sectional hospital-based survey.

作者信息

Treviño Ana, García Juan, de Mendoza Carmen, Benito Rafael, Aguilera Antonio, Ortíz de Lejarazu Raul, Ramos José M, Trigo Matilde, Eirós Jose M, Rodríguez-Iglesias Manuel, Torres Alvaro, Calderón Enrique, Hernandez Araceli, Gomez Cesar, Marcaida Goizane, Soriano Vincent

机构信息

Infectious Diseases Department, Hospital Carlos III, Madrid, Spain.

出版信息

AIDS Res Hum Retroviruses. 2010 Aug;26(8):861-4. doi: 10.1089/aid.2009.0234.

DOI:10.1089/aid.2009.0234
PMID:20672999
Abstract

The presence of antibodies to human T-lymphotropic virus (HTLV) types 1 and 2 was examined in 5742 sera belonging to consecutive adult outpatients attended during June 2008 at 13 different hospitals across Spain. Overall, 58.8% were female. Foreigners represented 8% of the study population. Seven individuals were seropositive for HTLV-2 (overall prevalence 0.12%). No cases of HTLV-1 infection were found. All HTLV-2(+) subjects were Spanish natives, of whom six were coinfected with HIV-1 and five with hepatitis C virus (HCV). Moreover, all but one of the HTLV-2(+) subjects had been intravenous drug users. In summary, this cross-sectional survey suggests that the rate of HTLV infection in Spain is low, and is mostly represented by HTLV-2. Infected individuals are generally Spanish natives with a prior history of intravenous drug use and are coinfected with HIV-1 and/or HCV.

摘要

对2008年6月期间西班牙13家不同医院连续收治的5742名成年门诊患者的血清进行了检测,以确定是否存在针对1型和2型人类嗜T淋巴细胞病毒(HTLV)的抗体。总体而言,58.8%为女性。外国人占研究人群的8%。7人HTLV-2血清学阳性(总体患病率0.12%)。未发现HTLV-1感染病例。所有HTLV-2阳性受试者均为西班牙本地人,其中6人同时感染HIV-1,5人同时感染丙型肝炎病毒(HCV)。此外,除1名HTLV-2阳性受试者外,其余均有静脉吸毒史。总之,这项横断面调查表明,西班牙的HTLV感染率较低,且大多为HTLV-2感染。感染个体通常为有静脉吸毒史的西班牙本地人,并同时感染HIV-1和/或HCV。

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