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[采用分级体力负荷评估高血压患者的治疗效果]

[Evaluation of therapy effectiveness in patients with hypertension using graded physical load].

作者信息

Anshelevich Iu V, Gersamia A G

出版信息

Klin Med (Mosk). 1991 Mar;69(3):38-41.

PMID:2067332
Abstract

J. W. Franz graded exercise test (GET) was employed to examine healthy subjects, untreated patients with stage I and II essential hypertension and hypertensive subjects treated with hydrochlorthiazide, alpha-methyldopa, prazosine, dilthiazem resultant in normal resting values of blood pressure. Hydrochlorthiazide did not protect the patients from a pathological hypertensive response to GET, whereas alpha-methyldopa and prazosine furnish a physiological hypertensive response in much less number of patients and dilthiazem made possible normal response in the majority of treated patients. GET is suggested for assessing effectiveness of hypertension treatment and individual choice of antihypertensive drugs.

摘要

采用J.W. 弗兰兹分级运动试验(GET)对健康受试者、未经治疗的I期和II期原发性高血压患者以及服用氢氯噻嗪、α-甲基多巴、哌唑嗪、地尔硫䓬且静息血压值正常的高血压患者进行检查。氢氯噻嗪未能保护患者免受GET引起的病理性高血压反应,而α-甲基多巴和哌唑嗪在较少患者中引起生理性高血压反应,地尔硫䓬使大多数接受治疗的患者有可能出现正常反应。建议采用GET来评估高血压治疗效果以及抗高血压药物的个体化选择。

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