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["食管性"心绞痛与心绞痛]

["Esophageal" angina and angina pectoris].

作者信息

Bortolotti M, Labriola E, Sarti P, Brunelli F, Mazza M, Barbara L

机构信息

Clinica Medica I, Università di Bologna.

出版信息

Minerva Chir. 1991 Apr 15;46(7 Suppl):145-52.

PMID:2067672
Abstract

In the last few years the non cardiac angina-like chest pain has encompassed more and more agitation not only in many patients but also in cardiologists, gastroenterologists and psychologists, as it involves socio-economic, pathophysiologic and therapeutic problems. The socio-economic aspect is well explained by the fact that in the USA at least 200,000 patients a year suffering from non cardiac angina-like chest pain, even when coronary arteriography has demonstrated normal coronary vessels, nevertheless continue to require cardiologic examinations and, if no one has clearly demonstrated the origin of their pain, they continue to live as invalids in constant fear of myocardial infarction. The discovery that the esophagus may be one of the causes of chest pain in these patients presenting with a previous diagnosis of "atypical" angina pectoris, unfortunately cannot resolve definitively the problem. An association of esophageal angina in patients with angina pectoris treated for long periods of time with Ca-antagonists and nitroderivatives has been described. In addition, the provocative or spontaneous tests to demonstrate the esophageal origin of chest pain give only a "likely" and not a "definite" diagnosis of esophageal angina. This also means to no "gold standard" text exist. Lastly, the "likely" diagnosis of esophageal angina is made in only about 50% of patients leaving the problem of the remaining 50% unanswered. These uncertainties induce some psychologists to assert that the cause of non cardiac angina-like chest pain is in the head ("panic disorder") and not in the esophagus, where the observed motor disorders should be an epiphenomenon.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

在过去几年中,非心源性心绞痛样胸痛不仅困扰着众多患者,也让心脏病专家、胃肠病专家和心理学家愈发感到棘手,因为它涉及社会经济、病理生理和治疗等诸多问题。社会经济方面的情况可由以下事实充分说明:在美国,每年至少有20万患有非心源性心绞痛样胸痛的患者,即便冠状动脉造影显示冠状动脉血管正常,仍继续需要进行心脏检查;而且,如果没有人能明确其疼痛的根源,他们会一直以患者身份生活,始终担心会发生心肌梗死。遗憾的是,发现食管可能是这些先前被诊断为“非典型”心绞痛患者胸痛的病因之一,并不能彻底解决问题。已有报道称,长期使用钙拮抗剂和硝基衍生物治疗的心绞痛患者中存在食管性心绞痛。此外,用于证明胸痛源于食管的激发试验或自发试验,只能给出食管性心绞痛的“可能”而非“确定”诊断。这也意味着不存在“金标准”检测方法。最后,只有约50%的患者能被“可能”诊断为食管性心绞痛,其余50%患者的问题仍未得到解答。这些不确定性致使一些心理学家断言,非心源性心绞痛样胸痛的病因在于脑部(“惊恐障碍”),而非食管,食管中观察到的运动障碍应是一种附带现象。(摘要截选至250词)

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