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[食管性胸痛患者的诊断评估:我们的经验]

[Diagnostic evaluation of the patient with esophageal chest pain: our experience].

作者信息

Bovero E, Poletti M, De Iaco F, Torre F

机构信息

Divisione di Gastroenterologia ed Endoscopia Digestiva, Ospedale San Martino, Genova.

出版信息

Minerva Chir. 1991 Apr 15;46(7 Suppl):157-62.

PMID:2067674
Abstract

Our experience in the field of the "cardio-esophageal" differential diagnosis of angina-like pain derives from the close cooperation between the Divisions of Gastroenterology and Cardiology. Commonly applied tests of esophageal function, always performed during electrocardiographic monitoring, are prolonged gastro-esophageal pH monitoring plus the adoption, as provocative tests, of the stress test in the course pH monitoring, of endo-esophageal distension and of electrostimulation in the course of manometry. An evaluation of prolonged pH monitoring tracings is performed not solely to locate a quantitatively pathological reflux, but especially to identify temporal correlations between the symptoms and the reflux. This explains how we were able to relate pain to reflux in 63% of the patients who took the test. Furthermore, use of esophagogastric monitoring makes it possible to identify the critical share of the non-acid reflux, i.e. mixed (21%) or alkaline (6%). Episodes of non-acid reflux feature a significantly higher rate of association with pain than acid reflux (12.5% of symptomatic acid refluxes, versus 6% of symptomatic acid refluxes, versus 6% of mixed refluxes and 7.15% of alkaline refluxes). Execution of an ergometric test, performed according to routine cardiologic procedures during pH monitoring, constitutes a valid stimulation for reflux-dependent pain, enabling us to achieve a diagnostic gain of 15.5% compared to pH monitoring alone. As stated, elicitation of pain by motor causes is performed using endo-esophageal distension (positive in 30% of cases) and with electrostimulation, a new test studied at our center.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

我们在“心-食管”类心绞痛样疼痛鉴别诊断领域的经验源于胃肠病学和心脏病学部门之间的密切合作。常用的食管功能测试,总是在心电图监测期间进行,包括延长的胃食管pH监测,以及在pH监测过程中采用应激测试、食管内扩张和测压过程中的电刺激作为激发试验。对延长的pH监测记录进行评估,不仅是为了确定定量的病理性反流,尤其是为了识别症状与反流之间的时间相关性。这就解释了为什么我们能够在63%接受测试的患者中将疼痛与反流联系起来。此外,使用食管胃监测可以识别非酸性反流的关键比例,即混合性(21%)或碱性(6%)。非酸性反流发作与疼痛的关联率明显高于酸性反流(有症状的酸性反流为12.5%,混合性反流为6%,碱性反流为7.15%)。在pH监测期间按照常规心脏病学程序进行的运动试验,对反流依赖性疼痛构成有效的刺激,与单独的pH监测相比,使我们的诊断准确率提高了15.5%。如前所述,通过食管内扩张(30%的病例呈阳性)和电刺激来诱发运动性疼痛,电刺激是我们中心研究的一项新测试。(摘要截短于250字)

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