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病例系列:切除术后液体硅胶凝胶对瘢痕外观影响的评估——一项初步研究。

Case series: evaluation of a liquid silicone gel on scar appearance following excisional surgery--a pilot study.

作者信息

Spencer James M

机构信息

Mount Sinai School of Medicine, New York, NY, USA.

出版信息

J Drugs Dermatol. 2010 Jul;9(7):856-8.

PMID:20677544
Abstract

Efforts to improve the size and appearance of scars have included therapies as varied as laser treatments and onion extract gels. Silicone gel sheeting is well know to improve the appearance of hypertrophic scars, and may have a role in the management of routine surgical and traumatic scars. By varying the degree of cross linking, silicone elastomer can be a solid sheet or a liquid gel. In this pilot series, seven patients applied a liquid silicone gel twice a day to one half of a new surgical scar for three months. At the end of this time, the treated side was noticeably better in appearance in five of seven patients while two of seven had no difference. In no patient was the silicone treated side worse in appearance.

摘要

改善疤痕大小和外观的方法包括多种疗法,如激光治疗和洋葱提取物凝胶。众所周知,硅胶片可改善增生性疤痕的外观,并且在常规手术和创伤性疤痕的处理中可能发挥作用。通过改变交联程度,硅酮弹性体可以制成固体片或液体凝胶。在这个试点系列中,七名患者每天两次将液体硅胶凝胶涂抹于一条新手术疤痕的一半上,持续三个月。在这段时间结束时,七名患者中有五名患者的治疗侧外观明显改善,而七名患者中有两名没有差异。没有一名患者的硅胶治疗侧外观变差。

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Case series: evaluation of a liquid silicone gel on scar appearance following excisional surgery--a pilot study.病例系列:切除术后液体硅胶凝胶对瘢痕外观影响的评估——一项初步研究。
J Drugs Dermatol. 2010 Jul;9(7):856-8.
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引用本文的文献

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Dermatol Ther (Heidelb). 2014 Dec;4(2):187-95. doi: 10.1007/s13555-014-0055-0. Epub 2014 Jun 25.
2
Efficacy and safety of an advanced formula silicone gel for prevention of post-operative scars.一种先进配方的硅凝胶预防术后瘢痕的疗效和安全性。
Dermatol Ther (Heidelb). 2013 Dec;3(2):157-67. doi: 10.1007/s13555-013-0036-8. Epub 2013 Nov 20.