[经支气管针吸活检术及支气管内超声引导下经支气管针吸活检术对肺癌患者肺门及纵隔淋巴结的诊断价值]
[Diagnostic value of transbronchial needle aspiration and endobronchial ultrasound-guided transbronchial needle aspiration for hilar and mediastinal lymph nodes in lung cancer patients].
作者信息
Zhang Song, Yi Hongli, Jiang Shujuan, Li Yuantang, Wang Yongkang
机构信息
Department of Respiratory Medicine, Provincial Hospital Affiliated to Shandong University, Jinan 250021, China.
出版信息
Zhongguo Fei Ai Za Zhi. 2010 May;13(5):447-50. doi: 10.3779/j.issn.1009-3419.2010.05.13.
BACKGROUND AND OBJECTIVE
Transbronchial needle aspiration (TBNA) and endobronchial ultrasound-guided TBNA (EBUS-TBNA) have been applied to the diagnosis for mediastinal lymph nodes. The aim of this study is to evaluate the clinical value and safety of TBNA and EBUS-TBNA on hilar and mediastinal lymph nodes of lung cancer patients.
METHODS
Two hundred fifty patients with suspected lung cancer were enrolled. All petients with hilar and/or m lymphoadenopa-ediastinal thy found by CT scan received TBNA, biopsy and brushing. EBUS-TBNA was performed in 15 patients among them.
RESULTS
Lung cancer were confirmed in 180 patients by TBNA, biopsy and brushing. The positive rates were 82.86%, 51.24% and 45.45%. Fifteen patients after EBUS-TBNA had a positive rate of 91.67%.
CONCLUSION
TBNA and EBUS-TBNA were proved to be safe procedure with a high yield for the diagnosis ofhilar and mediastinal lymph nodes in lung cancer patients.
背景与目的
经支气管针吸活检术（TBNA）和超声支气管镜引导下经支气管针吸活检术（EBUS-TBNA）已应用于纵隔淋巴结的诊断。本研究旨在评估TBNA和EBUS-TBNA对肺癌患者肺门和纵隔淋巴结的临床诊断价值及安全性。
方法
纳入250例疑似肺癌患者。所有经CT扫描发现有肺门和/或纵隔淋巴结肿大的患者均接受TBNA、活检及刷检。其中15例患者接受了EBUS-TBNA。
结果
通过TBNA、活检及刷检确诊肺癌180例。阳性率分别为82.86%、51.24%和45.45%。15例行EBUS-TBNA的患者阳性率为91.67%。
结论
TBNA和EBUS-TBNA被证明是诊断肺癌患者肺门和纵隔淋巴结安全且阳性率高的方法。
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