Migdał K, Korzeniowski S, Skołyszewski J
Kliniki Radioterapii Centrum Onkologii Instytutu im. Marii Skodowskiej-Curie, Oddział, Krakowie.
Otolaryngol Pol. 1991;45(2):85-9.
Results of combined treatment with the use of induction chemotherapy with cisplatinum and 5-fluorouracil in 28 patients with advanced squamous cell head and neck cancer are presented. Treatment schedule included cisplatinum 100 mg/m2 i.v. in day 1 and 5-fluorouracil 100 mg/m2/24 hour in days 1-5. Complete or partial regression was observed in 15 patients (53%) Radical radiotherapy was subsequently used in 18 patients and 6 were irradiated palliatively++. One year symptom-free survival was achieved in 10 patients (36%).
本文介绍了28例晚期头颈部鳞状细胞癌患者采用顺铂和5-氟尿嘧啶进行诱导化疗的联合治疗结果。治疗方案包括第1天静脉注射顺铂100mg/m²，第1 - 5天静脉滴注5-氟尿嘧啶100mg/m²/24小时。15例患者（53%）观察到完全或部分缓解。随后，18例患者接受了根治性放疗，6例接受了姑息性放疗。10例患者（36%）实现了1年无瘤生存。
