Imai S, Sone S, Sakai F, Aoki J, Kasuga T, Oguchi K, Tanizaki Y, Miyatake M, Ooki H
Department of Radiology, Shinshu University School of Medicine.
Nihon Igaku Hoshasen Gakkai Zasshi. 1991 Apr 25;51(4):357-64.
This study is based on 135 magnetic resonance (MR) exams of 110 patients with wallerian degeneration of the pyramidal tract shown on MR images acquired on a mid field imaging scanner. The MR findings of wallerian degeneration were abnormal signal band along the course of the pyramidal tract and ipsilateral brain stem shrinkage. In all 110 cases an abnormal signal band was seen on T2-weighted spin-echo images, that is, a hypointense band in four exams between 30 days and 116 days after onset of symptoms, and hyperintense bands in 122 exams. The hyperintense signal on T2-weighted images was shown in most cases after 200 days from the onset. In one case a signal of the pyramidal tract showed a hyperintense band at 7 days, hypointense at 30 days, and hyperintense again at 123 days after onset. Sequential MR exams of another case showed gradual narrowing of the hyperintense signal band and progression of the ipsilateral brainstem shrinkage. The narrowing of the pyramidal tract and the ipsilateral brain stem shrinkage tended to be shown after 6 months from onset.(ABSTRACT TRUNCATED AT 250 WORDS)
本研究基于110例在中场成像扫描仪上获取的磁共振（MR）图像显示有锥体束华勒氏变性的患者的135次MR检查。锥体束华勒氏变性的MR表现为沿锥体束走行的异常信号带和同侧脑干萎缩。在所有110例病例中，在T2加权自旋回波图像上均可见异常信号带，即在症状出现后30天至116天之间的4次检查中为低信号带，在122次检查中为高信号带。T2加权图像上的高信号在大多数病例中在症状出现后200天显示。1例病例中，锥体束信号在症状出现后7天显示为高信号带，30天为低信号，123天再次为高信号。另一例病例的连续MR检查显示高信号带逐渐变窄，同侧脑干萎缩进展。锥体束变窄和同侧脑干萎缩倾向于在症状出现后6个月显示。（摘要截短于250字）
