Division of Gastroenterology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.
J Clin Gastroenterol. 2011 Jan;45(1):34-9. doi: 10.1097/MCG.0b013e3181e5d1c5.
The objective of this study was to assess the total effective dose of ionizing radiation from abdominal diagnostic imaging in patients with inflammatory bowel disease (IBD) over a 5-year period.
Radiation exposure from diagnostic imaging is becoming increasingly common in IBD patients, in part due the availability of computed tomography (CT). Increased risk of malignancy has been associated with radiation exposure.
This is a retrospective chart review. A university-based gastroenterology database was searched for patients with a diagnosis of Crohn's disease (CD) or ulcerative colitis (UC) seen between 2003 and 2008. The cumulative ionizing radiation exposure, expressed in milli-Sieverts (mSv), was then calculated from standard tables and by counting the number of abdominal imaging studies.
Patients with CD had higher cumulative radiation exposure from diagnostic imaging than patients with UC (14.3 ± 1.45 mSv/5-y period vs. 5.9 ± 0.81 mSv/5-y period, P=0.00003). Three-quarters of the radiation exposure in both CD and UC was from CT scans. Thirty-four percent (127 of 373) of CD patients had CT scans, compared with just 20% (37 of 182) of UC patients. Importantly, 7% of CD patients were exposed to high levels of radiation (>50 mSv/5 y), in contrast to none of the UC patients.
Patients with IBD, and especially CD patients, undergo frequent diagnostic imaging and thus significant exposure to ionizing radiation. This radiation exposure reaches high levels in 7% of CD patients, mainly from CT scanning. Efforts should be made to minimize the radiation exposure from diagnostic imaging by reducing either the number of studies or radiation dose in modalities with ionizing radiation.
本研究旨在评估 5 年内炎症性肠病（IBD）患者腹部诊断影像学的总有效电离辐射剂量。
诊断影像学的辐射暴露在 IBD 患者中越来越常见，部分原因是计算机断层扫描（CT）的应用。辐射暴露与恶性肿瘤风险增加相关。
这是一项回顾性图表研究。检索了 2003 年至 2008 年间在一家以大学为基础的胃肠病学数据库中诊断为克罗恩病（CD）或溃疡性结肠炎（UC）的患者。然后根据标准表格和腹部影像学研究的数量计算出累积的电离辐射暴露量（以毫希沃特（mSv）表示）。
与 UC 患者相比，CD 患者的诊断影像学累积辐射暴露更高（14.3 ± 1.45 mSv/5-y 期 vs. 5.9 ± 0.81 mSv/5-y 期，P=0.00003）。两种疾病中，75%的辐射暴露来自 CT 扫描。34%（127/373）的 CD 患者接受了 CT 扫描，而 UC 患者只有 20%（37/182）接受了 CT 扫描。重要的是，7%的 CD 患者暴露于高剂量辐射（>50 mSv/5 y），而 UC 患者则无一人。
IBD 患者，尤其是 CD 患者，经常进行诊断性影像学检查，因此会受到大量电离辐射。这种辐射暴露在 7%的 CD 患者中达到较高水平，主要来自 CT 扫描。应通过减少检查次数或降低具有电离辐射的影像学检查的辐射剂量，努力将诊断影像学的辐射暴露降至最低。
