Center for Health Promotion, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
J Neurogastroenterol Motil. 2010 Jul;16(3):315-8. doi: 10.5056/jnm.2010.16.3.315. Epub 2010 Jul 26.
Eosinophilic esophagitis (EoE) is a disorder characterized by isolated eosinophilic infiltration of the esophagus with esophageal symptoms. Although some patients with EoE are related to food hypersensitivity, it is hard to identify causative foods. This report describes a case of EoE with dysphagia. A 28-year-old man presented with dysphagia and substernal discomfort for 15 days. He had taken a protein complex for 2 months. Endoscopy showed several linear furrows and multiple mucosal nodularities on the lower and mid esophagus, and the biopsies of esophagus revealed marked eosinophil infiltration in the mucosa. The skin testing for the protein complex was positive. The patient was successfully treated with withholding treatment.
嗜酸性粒细胞性食管炎(EoE)是一种以食管孤立性嗜酸性粒细胞浸润和食管症状为特征的疾病。虽然一些 EoE 患者与食物过敏有关,但很难确定致病食物。本报告描述了一例伴吞咽困难的 EoE 病例。一名 28 岁男性因吞咽困难和胸骨后不适 15 天就诊。他曾服用蛋白复合物 2 个月。内镜检查显示食管下段和中段有几条线性皱襞和多个黏膜小结节,食管活检显示黏膜有明显的嗜酸性粒细胞浸润。该蛋白复合物的皮肤试验阳性。患者经停用该治疗后成功治疗。