Böhm J, Röder-Weber M, Höfler H, Kolben M
Institute of Pathology, Technical University of Munich, School of Medicine, FRG.
Pathol Res Pract. 1991 Mar;187(2-3):348-52; discussion 352-3. doi: 10.1016/S0344-0338(11)80801-0.
The stromal Leydig cell tumour of the ovary is a very rare benign neoplasm which usually occurs in postmenopausal women. Due to a significant production of androgens by the tumour, it is frequently associated with symptoms of virilization. To our knowledge only 7 cases have been reported in the literature, one of them with bilateral manifestation. We report an additional case affecting both ovaries in a 59-year-old nun with long-standing virilism, review the literature, and discuss the histomorphological features for differential diagnosis.
卵巢间质型莱迪希细胞瘤是一种非常罕见的良性肿瘤，通常发生于绝经后女性。由于肿瘤大量分泌雄激素，常伴有男性化症状。据我们所知，文献中仅报道过7例，其中1例为双侧发病。我们报告1例59岁患有长期男性化症状的修女双侧卵巢均受累的病例，回顾相关文献，并讨论其组织形态学特征以进行鉴别诊断。
