Department of Chemistry, Beijing Normal University, Beijing, 100875, China.
Chem Commun (Camb). 2010 Sep 14;46(34):6344-6. doi: 10.1039/c0cc00986e. Epub 2010 Aug 3.
The interactions of the metal ions Mg(2+), Zn(2+), Ni(2+), and Co(2+) with thin films of peptide nucleic acids (PNAs) were studied by electrochemical impedance spectroscopy (EIS), and the results show that Zn(2+), Ni(2+) and Co(2+) interacted favorably with the PNA film involving the backbone and the nucleobases with the exception of Mg(2+) for which the interaction with the backbone appears to be dominant.
通过电化学阻抗谱(EIS)研究了金属离子 Mg(2+)、Zn(2+)、Ni(2+) 和 Co(2+) 与肽核酸(PNA)薄膜的相互作用,结果表明 Zn(2+)、Ni(2+) 和 Co(2+) 与 PNA 薄膜相互作用良好,涉及到骨架和碱基,而 Mg(2+) 与骨架的相互作用似乎占主导地位。