School of Life Sciences, East China Normal University, 3663# Zhongshanbei Road, Shanghai 200062, People's Republic of China.
J Comp Physiol B. 2011 Jan;181(1):117-23. doi: 10.1007/s00360-010-0500-z. Epub 2010 Aug 1.
Cerebral blood flow (CBF) of a vespertilionid bat, Miniopterus fuliginosus (M. f.), and a pteropodid bat, Rousettus leschenaultii (R. l.) was measured non-invasively during induced hypothermia (37-10°C for M. f. and 37-24°C for R. l.) with perfusion-weighted magnetic resonance imaging. In both species, the average CBF was found to decrease with rectal temperature. The patterns of hypothermia-induced regional CBF changes, however, were different between the two species. In the pteropodid bat, the extent of CBF decrease at lower rectal temperature was similar in the cortex and thalamus, resulting in an unchanged thalamus/cortex CBF ratio. In contrast, the thalamus/cortex CBF ratio in the vespertilionid species increased progressively with decreasing rectal temperature (1.52 ± 0.14 at 37 ± 1°C vs. 2.28 ± 0.29 at 10 ± 1°C). These results suggest that the manner in which the two bat species cope with low body temperature may be reflected by a differential CBF regulation between thalamus and cortex.
利用灌注加权磁共振成像技术，我们对伏翼蝠（Miniopterus fuliginosus，M. f.）和菊头蝠（Rousettus leschenaultii，R. l.）在诱导性低温（M. f. 为 37-10°C，R. l. 为 37-24°C）期间的脑血流（CBF）进行了非侵入性测量。在这两个物种中，平均 CBF 均随直肠温度降低而下降。然而，两种蝙蝠的低温诱导区域性 CBF 变化模式存在差异。在菊头蝠中，较低直肠温度下 CBF 下降的程度在皮层和丘脑相似，导致丘脑/皮层 CBF 比值不变。相比之下，伏翼蝠的丘脑/皮层 CBF 比值随直肠温度的降低而逐渐升高（37±1°C 时为 1.52±0.14，10±1°C 时为 2.28±0.29）。这些结果表明，两种蝙蝠物种应对低温的方式可能反映在丘脑和皮层之间的 CBF 调节差异上。
