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心率变异性(HRV)与创伤后应激障碍(PTSD):一项初步研究。

Heart rate variability (HRV) and posttraumatic stress disorder (PTSD): a pilot study.

机构信息

Michael E. DeBakey Veterans Affair Medical Center, Houston, TX, USA.

出版信息

Appl Psychophysiol Biofeedback. 2011 Mar;36(1):27-35. doi: 10.1007/s10484-010-9141-y.

Abstract

Exposure to combat experiences is associated with increased risk of developing Post Traumatic Stress Disorder. Prolonged exposure therapy and cognitive processing therapy have garnered a significant amount of empirical support for PTSD treatment; however, they are not universally effective with some patients continuing to struggle with residual PTSD symptoms. Heart rate variability (HRV) is a measure of the autonomic nervous system functioning and reflects an individual's ability to adaptively cope with stress. A pilot study was undertaken to determine if veterans with PTSD (as measured by the Clinician-Administered PTSD Scale and the PTSD Checklist) would show significantly different HRV prior to an intervention at baseline compared to controls; specifically, to determine whether the HRV among veterans with PTSD is more depressed than that among veterans without PTSD. The study also aimed at assessing the feasibility, acceptability, and potential efficacy of providing HRV biofeedback as a treatment for PTSD. The findings suggest that implementing an HRV biofeedback as a treatment for PTSD is effective, feasible, and acceptable for veterans. Veterans with combat-related PTSD displayed significantly depressed HRV as compared to subjects without PTSD. When the veterans with PTSD were randomly assigned to receive either HRV biofeedback plus treatment as usual (TAU) or just TAU, the results indicated that HRV biofeedback significantly increased the HRV while reducing symptoms of PTSD. However, the TAU had no significant effect on either HRV or symptom reduction. A larger randomized control trial to validate these findings appears warranted.

摘要

接触战斗经历会增加患创伤后应激障碍的风险。长时间暴露疗法和认知加工疗法为 PTSD 的治疗提供了大量的实证支持;然而,它们并非对所有患者都有效,一些患者仍在与残留的 PTSD 症状作斗争。心率变异性(HRV)是自主神经系统功能的一种衡量标准,反映了个体适应压力的能力。一项初步研究旨在确定 PTSD 患者(通过临床医生管理的 PTSD 量表和 PTSD 检查表测量)在干预前的基线期是否会与对照组相比显示出明显不同的 HRV;具体来说,要确定 PTSD 患者的 HRV 是否比没有 PTSD 的患者更抑郁。该研究还旨在评估提供 HRV 生物反馈作为 PTSD 治疗的可行性、可接受性和潜在疗效。研究结果表明,将 HRV 生物反馈作为 PTSD 的一种治疗方法是有效的、可行的,并且对退伍军人是可以接受的。与没有 PTSD 的受试者相比,与战斗相关的 PTSD 退伍军人的 HRV 明显下降。当 PTSD 退伍军人被随机分配接受 HRV 生物反馈加常规治疗(TAU)或仅接受 TAU 时,结果表明 HRV 生物反馈显著增加了 HRV,同时降低了 PTSD 的症状。然而,TAU 对 HRV 或症状减轻均无显著影响。似乎有必要进行更大的随机对照试验来验证这些发现。

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