Department of Anesthesia, Critical Care, & Pain Medicine, Massachusetts General Hospital, 55 Fruit St, Jackson 458, Boston, MA 02114, USA.
Can J Anaesth. 2010 Oct;57(10):888-97. doi: 10.1007/s12630-010-9366-5. Epub 2010 Jul 31.
The incidence of hypoxemia in patients undergoing surgery is largely unknown and may have a clinical impact. The objective of this study was to determine the incidence of intraoperative hypoxemia in a large surgical population.
We performed a retrospective study of electronically recorded pulse oximetry data obtained from two large academic medical centres. All adults (age ≥ 16 yr) undergoing non-cardiac surgery during a three-year period at the two hospitals were included in the analysis. Our main outcome measure was the percentage of patients with episodes of hypoxemia (SpO(2) < 90) or severe hypoxemia (SpO(2) ≤ 85) for two minutes or longer during the intraoperative period (induction of anesthesia, surgery, and emergence).
We evaluated 95,407 electronic anesthesia records at the two hospitals. During the intraoperative period, 6.8% of patients had a hypoxemic event, and 3.5% of patients had a severely hypoxemic event of two consecutive minutes or longer. Seventy percent of the hypoxemic episodes occurred during either induction or emergence- time periods that represent 21% of the total intraoperative time. From induction to emergence, one episode of hypoxemia occurred every 28.9 hr, and one episode of severe hypoxemia occurred every 55.7 hr of intraoperative time.
Despite advances in monitoring technology, hypoxemia continues to occur commonly in the operating room and may be a serious safety concern because of its potential impact on end organ function and long-term outcomes. Further studies are needed to improve our understanding of the clinical impact of intraoperative hypoxemia and the strategies that will be most useful in minimizing its occurrence.
接受手术的患者发生低氧血症的发生率尚不清楚,但其可能具有临床影响。本研究旨在确定在大型手术人群中术中低氧血症的发生率。
我们对从两个大型学术医疗中心获得的电子记录脉搏血氧仪数据进行了回顾性研究。所有在这两个医院接受非心脏手术的成年人(年龄≥16 岁)均纳入分析。我们的主要观察指标是术中期间(麻醉诱导、手术和苏醒)存在低氧血症(SpO2<90%)或严重低氧血症(SpO2≤85%)持续两分钟或更长时间的患者比例。
我们对这两个医院的 95407 份电子麻醉记录进行了评估。术中期间,有 6.8%的患者发生了低氧血症事件,有 3.5%的患者发生了严重低氧血症事件,持续时间超过两分钟。70%的低氧血症事件发生在诱导或苏醒期间,这两个时间段占总术中时间的 21%。从诱导到苏醒,每 28.9 小时发生一次低氧血症事件,每 55.7 小时发生一次严重低氧血症事件。
尽管监测技术有所进步,但低氧血症在手术室中仍然很常见,且可能成为一个严重的安全隐患,因为其可能对终末器官功能和长期结局产生影响。需要进一步研究以提高我们对术中低氧血症的临床影响以及最有助于降低其发生率的策略的理解。