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埃塞俄比亚南部地区公立医院接受非心脏手术的老年患者术中心脏并发症的发生率及相关因素:2022/2023年多中心横断面研究

Magnitude and associated factors of intraoperative cardiac complications among geriatric patients who undergo non-cardiac surgery at public hospitals in the southern region of Ethiopia: a multi-center cross-sectional study in 2022/2023.

作者信息

Abdulmelik Amina, Tila Mebratu, Tekilu Takele, Debalkie Ashebir, Habtu Elias, Sintayehu Ashagrie, Dendir Getahun, Gordie Naol, Daniel Abel, Suleiman Obsa Mohammed

机构信息

School of Anesthesia, College of Health Science and Medicine, Wolaita Soddo University, Wolaita Soddo, Ethiopia.

School of Medical Laboratory, College of Medicine and Health Science, Wolaita Soddo University, Wolaita Soddo, Ethiopia.

出版信息

Front Med (Lausanne). 2024 Apr 17;11:1325358. doi: 10.3389/fmed.2024.1325358. eCollection 2024.

Abstract

BACKGROUND

Intraoperative cardiac complications are a common cause of morbidity and mortality in non-cardiac surgery. The risk of these complications increased with the average age increasing from 65. In a resource-limited setting, including our study area, the magnitude and associated factors of intraoperative cardiac complications have not been adequately investigated. The aim of this study was to assess the magnitude and associated factors of intraoperative cardiac complications among geriatric patients undergoing non-cardiac surgery.

METHODS

An institutional-based multi-center cross-sectional study was conducted on 304 geriatric patients at governmental hospitals in the southern region of Ethiopia, from 20 March 2022 to 25 August 2022. Data were collected by chart review and patient interviews. Epi Data version 4.6 and SPSS version 25 were used for analysis. The variables that had association ( < 0.25) were considered for multivariable logistic regression. A value < 0.05 was considered significant for association.

RESULT

The overall prevalence of intraoperative cardiac complications was 24.3%. Preoperative ST-segment elevation adjusted odds ratio (AOR = 2.43, CI =2.06-3.67), history of hypertension (AOR = 3.42, CI =2.02-6.08), intraoperative hypoxia (AOR = 3.5, CI = 2.07-6.23), intraoperative hypotension (AOR = 6.2 9, CI =3.51-10.94), age > 85 years (AOR = 6.01, CI = 5.12-12.21), and anesthesia time > 3 h (AOR =2.27, CI = 2.0.2-18.25) were factors significantly associated with intraoperative cardiac complications.

CONCLUSION

The magnitude of intraoperative cardiac complications was high among geriatric patients who had undergone non-cardiac surgery. The independent risk factors of intraoperative cardiac complications for this population included age > 85, ST-segment elevation, perioperative hypertension (stage 3 with regular treatment), duration of anesthesia >3 h, intraoperative hypoxia, and intraoperative hypotension. Holistic preoperative evaluation, optimization optimal and perioperative care for preventing perioperative risk factors listed above, and knowing all possible risk factors are suggested to reduce the occurrence of complications.

摘要

背景

术中心脏并发症是非心脏手术中发病和死亡的常见原因。随着平均年龄从65岁增加,这些并发症的风险也随之增加。在包括我们研究区域在内的资源有限的环境中,术中心脏并发症的严重程度和相关因素尚未得到充分研究。本研究的目的是评估老年非心脏手术患者术中心脏并发症的严重程度和相关因素。

方法

2022年3月20日至2022年8月25日,在埃塞俄比亚南部地区的政府医院对304名老年患者进行了一项基于机构的多中心横断面研究。通过病历审查和患者访谈收集数据。使用Epi Data 4.6版和SPSS 25版进行分析。将具有关联(<0.25)的变量纳入多变量逻辑回归分析。P值<0.05被认为具有显著关联。

结果

术中心脏并发症的总体患病率为24.3%。术前ST段抬高调整后的优势比(AOR = 2.43,CI = 2.06 - 3.67)、高血压病史(AOR = 3.42,CI = 2.02 - 6.08)、术中低氧血症(AOR = 3.5,CI = 2.07 - 6.23)、术中低血压(AOR = 6.29,CI = 3.51 - 10.94)、年龄>85岁(AOR = 6.01,CI = 5.12 - 12.21)以及麻醉时间>3小时(AOR = 2.27,CI = 2.02 - 18.25)是与术中心脏并发症显著相关的因素。

结论

老年非心脏手术患者术中心脏并发症的发生率较高。该人群术中心脏并发症的独立危险因素包括年龄>85岁、ST段抬高、围手术期高血压(规律治疗的3期)、麻醉持续时间>3小时、术中低氧血症和术中低血压。建议进行全面的术前评估、优化围手术期护理以预防上述围手术期危险因素,并了解所有可能的危险因素以减少并发症的发生。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dff2/11061426/65d51c6d6a53/fmed-11-1325358-g001.jpg

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